echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Digestive System Information > One picture summary: The treatment process of chronic constipation is clinically necessary

    One picture summary: The treatment process of chronic constipation is clinically necessary

    • Last Update: 2021-10-01
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com
    This article is compiled and compiled by Yimaitong, please do not reprint without authorization
    .

    Constipation is a common gastroenterology disease, but clinical examination and treatment procedures for constipation need to be further standardized
    .

    This article will introduce a flow chart for the treatment of constipation, which is derived from Gastroenterology (impact factor 19.
    233).
    The flow chart was created by two physicians Adil E.
    Bharucha and Brian E.
    Lacy from the Department of Digestion and Liver Diseases, Mayo Clinic, USA
    .

     The definition and current status of constipation Constipation is a (group) symptom, manifested as difficulty in defecation and/or reduced defecation frequency, dry and hard stool
    .

     Defecation difficulties include laborious defecation, difficulty in defecation, feeling of incomplete defecation, anorectal blockage, time-consuming defecation and the need for assisted defecation; reduced defecation frequency means less than 3 bowel movements per week
    .

    The course of chronic constipation is at least 6 months
    .

     Worldwide, chronic constipation (CC) is one of the most common gastrointestinal diseases, with a prevalence of 15%
    .

     According to the "Expert Consensus Opinions on Chronic Constipation in China (2019, Guangzhou)", the prevalence of chronic constipation among adults in China is 4.
    0% to 10.
    0%
    .

    The prevalence of chronic constipation increases with age, and the prevalence of women is higher than that of men
    .

     The hazards of chronic constipation ➤Constipation is closely related to anorectal diseases, such as hemorrhoids, anal fissure, and rectal prolapse; ➤Chronic constipation may be involved in colorectal cancer, hepatic encephalopathy, breast disease, Alzheimer's disease and other diseases Play an important role; ➤In acute myocardial infarction, cerebrovascular accidents and other diseases, excessive defecation may lead to aggravation and even death
    .

     Common clinically-related causes related to constipation 1.
    Drug action Drug-induced constipation is mainly induced by anticholinergic drugs, opioids, calcium antagonists, antidepressants, antihistamines, antispasmodics, and anticonvulsants.
    Specific as shown in Table 1, see the following: Table 1 Drugs that can cause constipation (picture from Gastroenterology) 5-HT, serotonin; a based on community research found to be related to constipation drugs; b may be related to electrolyte disorders
    .

     2.
    Mechanical obstruction ➤ Colon cancer; ➤ External compression caused by malignant lesions; ➤ Stricture (diverticulum or stenosis after ischemia); ➤ Rectal protrusion; ➤ Hirschsprung's colon; ➤ Anal fissure
    .

     There are usually alarm signs or abnormal laboratory examinations, and digital rectal examinations and abdominal X-rays can provide relevant hints
    .

     3.
    Abnormal metabolism ➤diabetes; ➤hypothyroidism; ➤hypercalcemia; ➤hypokalemia; ➤hypomagnesemia; ➤uremia, ➤heavy metal poisoning, ➤uremia
    .

     All of the above can be diagnosed by abnormal laboratory test results, but this laboratory test should only be performed when a particular disease is highly suspected (for example, in patients taking diuretics)
    .

     4.
    Myopathy ➤ Amyloidosis; ➤ Scleroderma
    .

     Patients often present other clinical features of these diseases
    .

     5.
    Neuropathy ➤Parkinson's disease; ➤ spinal cord injury; ➤ tumor; ➤ cerebrovascular disease; ➤ multiple sclerosis
    .

     In patients with these diseases, constipation (chronic transit and/or DD) is very common
    .

     Six other diseases depression, degenerative joint disease, autonomic neuropathy, cognitive impairment, heart disease and so on
    .

     These diseases themselves and/or medications used for these diseases may cause constipation
    .

    Chronic constipation "algorithm" flow chart Figure 1 CC processing algorithm (the figure is from Gastroenterology, developed by two Mayo Clinic doctors); CC, chronic constipation
    .

    (Click to view larger image) Reference source: [1]Bharucha AE,Lacy BE.
    Mechanisms, Evaluation, and Management of Chronic Constipation.
    Gastroenterology.
    2020, 158 (5) :1232-1249.
    e3.
    [2] Chinese Medical Association Digestion Gastrointestinal Dynamics Group, Functional Gastrointestinal Disease Cooperative Group of the Chinese Society of Diseases.
    Expert consensus on chronic constipation in China (2019, Guangzhou)[J].
    Chinese Journal of Digestion,2019,39(9):577-598.
    Contribution email: tougao@medlive.
    cn
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.