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At present, the industry-recognized Cellular and Gene Therapy (CGT, Cellular and Gene Therapy) refers to the transfer of certain genetic material to the specific target cells of the patient, and the modification of individual gene expression or gene expression through gene addition, gene modification, gene silencing, etc.
One treatment is expected to be cured for life
One treatment is expected to be cured for lifeUnlike most traditional chemical drugs and biological macromolecular drugs that target proteins, most CGT therapies directly target DNA, and treat diseases from the source by changing DNA, aiming at some serious and rare genetic diseases that are not cureable.
Supervision and quality standards and regulations promote the development of the industry
Supervision and quality standards and regulations promote the development of the industryIn 2016, 21-year-old college student Wei Zexi passed away after receiving immunotherapy without regulatory approval.
After this incident, led by the National Health Commission and the National Medical Products Administration, the reform of the domestic policy side was fully launched
The introduction of a series of domestic industry regulatory policies and treatment standards has gradually strengthened and improved the industry regulatory work in the field of CGT treatment, and also put forward specific and feasible technical requirements for the development of the industry.
Product form of CGT therapy
Product form of CGT therapySpecific to the product form, CGT therapy includes plasmid DNA, viral vectors, bacterial vectors, human gene editing technology, patient-derived cells, and gene therapy products
Source: public data compilation
The carrier is the most important part of CGT therapy
The carrier is the most important part of CGT therapyIt is particularly noteworthy that the carrier is the most important link in cell gene therapy
The development and production of CGT therapy mainly includes three links: plasmid production, viral vector production, and cell preparation
According to rough statistics, plasmids and viral vectors account for half of the current CGT treatment field
Abundant reserves of products under research are waiting for the industry to break out
Abundant reserves of products under research are waiting for the industry to break outCGT therapy is gradually transforming from basic scientific research to industrial application, and it is also widely recognized and valued by the market
According to reports, in the future, a large number of cell and gene therapy research projects will begin to focus on entering the clinical stage.
Note: The original text has been deleted