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Over 2 billion U.S. dollars to build breast cancer protein degradation therapy Pfizer/Arvinas reached cooperation

 Last Update: 2021-07-27
 Source: Internet
 Author: User

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On July 22, Pfizer and Arvinas jointly announced an agreement to jointly develop and promote the oral PROTAC protein degrading agent ARV-471 that targets the estrogen receptor (ER) under research

ARV-471 is a potential "best-in-class" ER degradation therapy

Among the 14 patients whose anti-cancer activity can be analyzed, one patient achieved confirmed partial remission, with a 51% reduction in tumor lesions

Arvinas and Pfizer expect to initiate two clinical trials of ARV-471 in 2021, including a second phase 1b clinical trial in combination with everolimus and a trial in the context of neoadjuvant therapy

Note: The original text has been deleted

Reference materials:

[1] Arvinas and Pfizer A nnounce Global Collaboration to Develop and Commercialize PROTAC® Protein Degrader ARV-471.

[2] Arvinas and Pfizer Announce Global Collaboration to Develop and Commercialize PROTAC® Protein Degrader ARV-471.
Retrieved July 22, 2021, from https://ir.
arvinas.
com/news-releases/news-release-details/arvinas- and-pfizer-announce-global-collaboration-develop-and

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