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Excessive consumption of high-fat foods can cause insulin signal failure in the brain, leading to obesity and diabetes, a new study has revealed.The study, published in the journal Biochemistry, tested how overeating affects insulin's ability to regulate fat breakdown in the brain, the insulin in the lower pasum, and found that eating large amounts of food disrupts insulin function in the brain, which in turn increases the metabolism of fat cells.led by Dr.
Christopher Buettner
of Mount Sinai School of Medicine in the United States, noted that insulin in the brain inhibits fat breakdown, in which fat is broken down and fatty acids are released. When this fat breakdown process is not controlled, levels of fatty acids in the body rise - which in turn can trigger and exacerbate obesity and type
2
diabetes."We'
why people who eat too much end up with diabetes," Buettner said. Our recent research shows that once you overeat, the brain produces insulin resistance.he explains: "Because insulin in the brain controls fat breakdown in adipose tissue by reducing the flow of the sensory nervous system to adipose tissue, insulin resistance in the brain increases fatty acids that spill from adipose tissue into the blood."the researchers explained that this uncontrolled release of fatty acids promotes lipid toxicity, characterized by inflammatory reactions and insulin resistance that cause and worsen diabetes.Fatty acids
increase glucose production in the liver, which increases blood sugar levels, Buettner explained." is a vicious circle, and as we all know, it may have started with overeating, and this study shows that the brain gets hurt first and then starts spiraling downwards. Forstudy Buettner
and his team fed rats -- including
10
percent lard -- on a high-fat diet for three days. This feeding method increased the daily calories by up to
50 percent compared to the control group that was regularly fed a low-fat
.team then injected a small amount of insulin into the brains of two groups of rats -- which previous studies have shown inhibits the release of glucose from the liver and fatty acids from adipose tissue., overeating impairs the brain's ability to suppress these effects in a normal way.Buettner
that overecuring in humans can have a similar effect -- which can be interpreted as the brain's insulin resistance mechanism.overeat, your brain becomes slow to respond to these important signals, such as insulin, which makes you on the path to diabetes, " he says. We believe that the effects that occur in mice will also occur in humans. ”