Pesticide industry is on the right track, product upgrading is accelerating

China is a big country in the production of pesticides, so the production and use of pesticides are also leading in the world.
However, there are not many high-efficiency pesticide products in China before, and the products have hardly been updated.
This is not conducive to the long-term development of pesticides.
Now the pesticide industry has finally gone.
On the right track, product upgrades began to accelerate
.
In recent years, the launch of China's pesticide creation products has accelerated significantly, and many new products such as ethoxystrobin, syringostrobin, zinc thiazole, toxafluphos, cyanostrobin, etc.
, have been promoted and used in the market increasing year by year
.
The bactericidal spectrum of various types of fungicides, such as pesticides and traditional bulk conventional products, are very different.
Many experts suggested that the same product can be transformed into a class of products through compounding and expanding the control spectrum, which can play a more important role.
Delay single agent resistance
.
Hot product change is accelerating, Professor Liu Xili, chairman of the Chemical Control Professional Committee of the Chinese Society of Phytopathology, introduced in her speech that chemical agents are a broad concept.
In addition to agents with antibacterial and bactericidal effects, they also include some plant immune activators and plant-derived pesticides.
Therefore, the rational and synergistic use of different control measures and different types of agents is of great significance to the improvement of disease prevention and control, the enhancement of efficiency, and the reduction of chemical agents
.
According to experts, since the 1960s, the representatives have been chlorinate and carbendazim; in the 1970s, there were metalaxyl and procymidone, which have dual functions of protection and treatment
.
In the 1980s, triazole products such as epoxiconazole and tebuconazole have their own characteristics.
For example, the epoxiconazole series has good protection, treatment and eradication activities against cereal crop diseases, and has systemic activity; and triazole Although ketone has a narrow bactericidal spectrum, it has the effects of preventing, eradicating and curing diseases such as black disease, rust and powdery mildew
.
Fungicides in the 1990s were represented by products such as azoxystrobin and flumorph
.
Among them, azoxystrobin is a typical representative of methacrylic acid ester fungicides.
It is known for its high efficiency and broad spectrum.
It is resistant to almost all fungi such as powdery mildew, rust, glume blight, net spot, downy mildew, rice blast, etc.
Diseases have good activity
.
After that, the senostam launched by the Shenhua Hospital has a broad bactericidal spectrum, high activity, preventive and therapeutic effects, and has good compatibility with environmental organisms.
It is resistant to flagella, zygosity, ascomycetes, basidiomycetes and deuteromycetes.
A variety of plant diseases caused by it have a good control effect, at the same time, it has a significant improvement effect on crop growth traits and quality, and can increase yield
.
After entering the 21st century, difenoconazole and fluconazole are on the market, winning strong responses in the fungicide market
.
Difenoconazole, which is relatively safe among triazole fungicides, is a systemic product with protective and therapeutic effects
.
It is widely used in fruit trees, vegetables and other crops, and can effectively prevent diseases such as scab, spotted leaf disease, powdery mildew, brown spot, rust, and head blight
.
Fluconazole is a formamide fungicide.
Through foliar spraying and seed treatment, it has a good control effect on more than 20 kinds of fungal diseases such as sheath blight, gray mold and summer spot
.
Guan Aiying, a senior engineer at the Shenyang Research Institute of Chemical Industry, said that there are 50 pesticide varieties created in China, including 20 fungicides, 17 insecticides and acaricides, 7 herbicides, 1 antiviral agent and 4 PGRs
.
And Liu Chang made the new drug innovation team innovate metalaxyl analogues? ? ? Natural product cinnamamide fungicide, dimethomorph analogue? ? ? Fungicide-related products such as flumorph and its intermediate parafluorobenzoic acid; later developed pyraclostrobin, syringomycin and pyraclostrobin and other fungicides, as well as β-keto acid esters as raw materials for pyrimidinamine series sterilization Agent
.
(See Table 1) In the process of pesticide creation, the direct synthesis method, substitution method and derivative method invented by Teacher Liu Changling of Shenhua Institute have greatly improved the efficiency and success rate of new drug creation
.
Among them, the creation of syringomycin is very representative.
The product contains two natural product fragments consisting of only three elements: carbon, hydrogen, and oxygen.
It is resistant to apple rot, rice sheath blight, rice blast and wheat head blight.
It has a good control effect.
The experimental results in an area of ​​45 apples per hectare show that the control effect can reach 80%
.
Moreover, the production data of syringomycin on rice and wheat showed that the yield increased by more than 10%
.
Looking at the domestic and foreign market of fungicides, succinate dehydrogenase inhibitor fungicides are the fastest growing type of fungicides
.
Most of the fungicides worthy of attention are concentrated in multinational companies.
BASF’s fluconazole has excellent control effects against diseases on cereals, soybeans, corn and rape, and has excellent systemic conduction activity.
It can be used for foliar sprays, Seed treatment; Syngenta's benzodifluconazole has a special effect on Asian soybean rust, and also has a good control effect on wheat leaf blight, peanut black spot, wheat rot and wheat base rot.
It is especially effective for wheat powdery mildew, corn spot disease and gray mold, and can be compounded with a variety of fungicides without cross-resistance
.
Bayer's fluoxastrobin has a wide application period.
It can provide good protection and treatment to crops in the early stages of fungal infection, such as spore germination, germ tube growth, and immersion into the leaves, or in the hyphae growth period, and can provide good protection and treatment for spore germination.
It is the most effective at the initial stage; it also has excellent systemic activity and good resistance to rain erosion.
It can be used for foliar spray or seed treatment
.