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Pfizer deploys innovative protein degradation technology to selectively target tumor tissues

 Last Update: 2022-01-01
 Source: Internet
 Author: User

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On November 29, 2021, Ranok Therapeutics announced an agreement with Pfizer to use the company’s proprietary molecular chaperone-mediated targeted protein degradation (CHAMP) technology platform to target an undisclosed Of cancer targets to develop innovative therapies

In recent years, targeted protein degradation has become a new direction in the development of small molecule drugs

In some cases, the chaperone can bind to E3 ubiquitin ligase and mediate the degradation of the substrate by the proteasome

▲Principle of CHAMP technology platform (picture source: Shunuo Biological official website)

Through this platform, Pinnacle Biosciences develops innovative drugs needed for tumors and other major diseases, improves the long-term quality of life of patients, and satisfies unmet clinical needs.

Reference materials:

[1] Ranok Therapeutics Announces Agreement with Pfizer on Targeted Protein Degradation.

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