Pfizer oral anti-corona drug Phase 2/3 trial results released: reduce the risk of severe death by 89%

On November 5th, local time, Pfizer announced the results of its oral anti-coronavirus candidate drug Phase 2/3 trial: Compared with the placebo group, the drug can treat non-hospitalized adult patients with severe new coronary pneumonia during the 28-day study period.
The risk of hospitalization or death was reduced by 89%
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Based on the recommendations of the US Independent Data Monitoring Committee and in consultation with the US Food and Drug Administration (FDA), Pfizer has stopped further research because these results show overwhelming efficacy
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Pfizer said it is submitting an emergency use authorization (EUA) for the drug to the FDA as soon as possible
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According to Reuters, Pfizer’s test results appear to be better than those of Merck’s similar drug Molnupiravir (Molnupiravir)
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According to a report released last month, the risk of death or hospitalization for severely ill high-risk patients taking monabigravir is reduced by 50%
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Neither company has provided complete test data yet
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Pfizer’s new drug is used in combination with an antiviral drug called Ritonavir, and this combined treatment program is called Paxlovid
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Patients receiving this course of treatment take three pills at a time, twice a day
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Pfizer analyzed the hospitalization or death of 1,219 patients diagnosed with mild to moderate new coronary pneumonia.
They have at least one risk factor for severe illness, such as obesity or older age
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The study found that 0.
8% of subjects who took Paxlovid within three days of the onset of symptoms were hospitalized, and no one died within 28 days of treatment
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In contrast, the hospitalization rate of patients taking placebo (placebo) was 7%, and 7 of them died
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The hospitalization rate for patients receiving treatment within five days of the onset of symptoms was similar, with 1% of the treated patients being hospitalized; while the placebo group had 6.
7%, including 10 deaths
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