-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Pharmaceutical grade borneol (synthetic) Pharmacopoeia standard borneol is easily absorbed through the mucosa and subcutaneous tissue, and is excreted after combining with glucuronic acid in the body
.
3H-borneol at 1μCi/(g body weight) can be rapidly absorbed through the intestinal mucosa when given to mice by gavage.
It can pass through the blood-brain barrier within 5 minutes of administration, and has a higher concentration and longer residence time in the central nervous system.
Its orifice effect may be related to it
.
Borneol can maintain a high blood drug concentration in the blood for a long time, and it is eliminated quickly by the liver and kidney, and it is not easy to accumulate
.
The distribution half-life of 3H-borneol 2.
6μCi/mice by intravenous injection is 2.
8min, mainly in the heart, lung, liver, kidney,
etc.
3.
5μCi/gavage, the half-absorption period was 0.
157 hours, and the absorption coefficient was 0.
25, indicating that the bioavailability was poor; the elimination half-life was 5.
3 hours, and it was not easy to accumulate
.
Resin processed products, or the crystallization of borneol incense trunks obtained by distillation and cooling, is called "borneol borneol", also known as "plum slices"
.
It is made from the sublime of the leaves of Blumea balsamifera DC.
, a perennial herb of the Compositae family, which is processed and chopped, and is called "mugwort"
.
Turpentine, camphor, etc.
are now mostly used, which are synthesized by chemical methods, and are called "mechanism borneol"
.
The finished borneol must be stored in a cool place and sealed
.
For grinding powder
.
The chemical composition is a terpene, the molecular formula is C10H18O, also known as borneol or 2-camphenol
.
White translucent hexagonal crystals with a camphor-like smell
.
D-borneol is leaf-like or hexagonal flake crystal; melting point 208℃, boiling point 212℃, relative density 1.
011 (20/4℃), specific rotation +37.
7 (ethanol); soluble in ethanol and benzene
.
L-borneol is a hexagonal flake crystal; melting point is 208.
6°C, boiling point is 210°C (779 mm Hg), relative density is 1.
1011 (20/4°C); soluble in ethanol, acetone and benzene
.
Racemic borneol is leaf-like crystal; melting point is 210.
5℃, easy to sublime, relative density is 1.
011 (20/4℃); soluble in ethanol and benzene
.
Camphor is formed when oxidized
.
Borneol can be obtained by reducing camphor with sodium metal in ethanol solution; or by esterifying pinene with oxalate in the presence of a catalyst and then hydrolyzing it
.
Borneol is widely used in the preparation of rosemary, lavender-type flavors, and in traditional Chinese medicine and Chinese ink
.
.
3H-borneol at 1μCi/(g body weight) can be rapidly absorbed through the intestinal mucosa when given to mice by gavage.
It can pass through the blood-brain barrier within 5 minutes of administration, and has a higher concentration and longer residence time in the central nervous system.
Its orifice effect may be related to it
.
Borneol can maintain a high blood drug concentration in the blood for a long time, and it is eliminated quickly by the liver and kidney, and it is not easy to accumulate
.
The distribution half-life of 3H-borneol 2.
6μCi/mice by intravenous injection is 2.
8min, mainly in the heart, lung, liver, kidney,
etc.
3.
5μCi/gavage, the half-absorption period was 0.
157 hours, and the absorption coefficient was 0.
25, indicating that the bioavailability was poor; the elimination half-life was 5.
3 hours, and it was not easy to accumulate
.
Resin processed products, or the crystallization of borneol incense trunks obtained by distillation and cooling, is called "borneol borneol", also known as "plum slices"
.
It is made from the sublime of the leaves of Blumea balsamifera DC.
, a perennial herb of the Compositae family, which is processed and chopped, and is called "mugwort"
.
Turpentine, camphor, etc.
are now mostly used, which are synthesized by chemical methods, and are called "mechanism borneol"
.
The finished borneol must be stored in a cool place and sealed
.
For grinding powder
.
The chemical composition is a terpene, the molecular formula is C10H18O, also known as borneol or 2-camphenol
.
White translucent hexagonal crystals with a camphor-like smell
.
D-borneol is leaf-like or hexagonal flake crystal; melting point 208℃, boiling point 212℃, relative density 1.
011 (20/4℃), specific rotation +37.
7 (ethanol); soluble in ethanol and benzene
.
L-borneol is a hexagonal flake crystal; melting point is 208.
6°C, boiling point is 210°C (779 mm Hg), relative density is 1.
1011 (20/4°C); soluble in ethanol, acetone and benzene
.
Racemic borneol is leaf-like crystal; melting point is 210.
5℃, easy to sublime, relative density is 1.
011 (20/4℃); soluble in ethanol and benzene
.
Camphor is formed when oxidized
.
Borneol can be obtained by reducing camphor with sodium metal in ethanol solution; or by esterifying pinene with oxalate in the presence of a catalyst and then hydrolyzing it
.
Borneol is widely used in the preparation of rosemary, lavender-type flavors, and in traditional Chinese medicine and Chinese ink
.
