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    Home > Picture description document @ nature energy, I will save you with microorganism!

    Picture description document @ nature energy, I will save you with microorganism!

    • Last Update: 2017-06-01
    • Source: Internet
    • Author: User
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    Methane catalyst -- the biosynthesis of coenzyme f 430 (http://www.nature.com/doifner/10.1038/nature21427; doi: 10.1038/nature21427) Highlights: 1) new gene cluster CFB was found to participate in coenzyme f 430 biosynthesis; 2) coenzyme f 430 was identified Fig 1: coenzyme F430 and green energy Energy, improving the living conditions of human beings, providing the progress of science and technology, is also the main culprit of greenhouse effect It can be said that half is Buddha and half is devil Microorganism: maybe it can open a gap for energy utilization Recently, the international famous journal Nature published the latest research results of Professor Martin Warren's scientific research team at the University of Kent, England: we found the biosynthesis pathway of coenzyme f 430, an auxiliary component regulating methane biosynthesis in methanogens Coenzyme f 430 is bright yellow (see Fig 1) It is similar to heme in red blood cells and chlorophyll in plants in structure It can absorb carbon dioxide and convert it into methane The results show that the starting molecule of coenzyme f 430 biosynthesis is sirohydrochlorin, and the enzyme catalytic system is cfba-cfbe The key of this process is to insert Ni 2 + into the coenzyme center Using a series of experimental methods, the researchers expressed the CFB enzyme system in vitro, identified the related intermediates, and established the biosynthesis pathway of coenzyme f 430 (see Figure 2) This is a step closer to the further heterologous expression of methane biosynthesis gene cluster and the efficient utilization of energy in the future Figure 2: biosynthesiosof coenzyme f 430 from sirohydrochlorin If the methane biosynthesis gene cluster is successfully transferred into the engineering strain, it can produce methane in quantity and realize energy regeneration There are microbes to help us deal with carbon dioxide, but also to provide us with energy, science, worthy of our thinking! Previous recommendations of biosynthesis series: 1 Laying eggs on the back of chickens, expanding the capacity of lincomamide compound library by enzyme catalysis 2 Biosynthesis of sterol like natural products in unusual ways 3 Magic hand, finding out hidden compounds 4 Biosynthesis of anisomycin, a pyrrolidine protein synthesis inhibitor: new gene integration and hidden biosynthesis steps Note: due to the limited ability of the author, please leave a message if there are any questionable points above, and we will contact you actively! Reprint please indicate: CBG information, Tao Xiaohua Welcome to the "CBG information" WeChat official account and QQ group: 498263368 (click join to join CBG- [biosynthesis]: https://jq.qq.com/ _wv=1027&k=49bs909, enter the secret number: Name + unit or research direction)
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