PLoS ONE: Deaths or higher from COVID-19 infection in smokers and patients with chronic obstructive pulmonary disease

2020 May 17 News /BioValleyBIOON / - Recently, a publication entitled International Journal onPLoSONE"Prevalence, SeverityandMortalityassociatedwithCOPDandSmokinginpatientswithCOVID-19: ARapidSystematicReviewandMeta-Analysi" research report, scientists from University College London and other institutions through the study found that current smokers and chronic obstructive pulmonary disease (COPD) mortality due to COVID-19 infection higher, but there is a higher risk of serious complicationsSource:CC0PublicDomainCOPD is a common, and the body airflow limitation associated with persistent pulmonary dysfunction, it is estimated that around the world there are 251 million people will be affected with COPD, due to the SARS-CoV-2 respiratory coronavirus the body will have some impact, the study, the researchers wanted to understand COVID 19-by studying patients with COPD prevalence and effects Happeningarticle, the researchers systematically searched the relevant scientific literature database, to find COVID-19 epidemiology, clinical features and the literature on COPD prevalence COVID-19 patients, Finally, the researchers screened 123 potentially relevant articles out of 15 studies meet the quality and research into the guidelines, a total of 2473 confirmed COVID 19-patient included in the study, in which 2.3% (58) of the patients at the same time suffering from COPD, 9% (221 names) of the patients were smokersCOVID-19 have COPD patients with severe risk for severe disease 63% risk of mortality of 60% without the risk of COPD COVID-19 in patients suffering from severe to severe disease 33.4% ( RR1.88,95% CI1.4-2.4), mortality was 55% (RR1.1,95% CI0.6-1.8); in addition, and people who had never smoked, compared with the previous, current smokers severe the potential for complications is 1.45 times (95% CI1.03-2.04) of the formerFor this study, the researchers did not analyze whether there is a correlation between the severity of COPD exacerbation frequency whether or COVID-19 with COPD prognosis or complications, because of the location included in the study, there are some differences in the environment and design, so the results will also be affected and related restrictions(Biovalley Bioon.com) Original source:JaberS.Alqahtani, TopeOyelade, AbdulelahM.Aldhahir, etalPrevalence, SeverityandMortalityassociatedwithCOPDandSmokinginpatientswithCOVID-19: ARapidSystematicReviewandMeta- Analysis,PLOSONE (2020) .doi: 10.1371 / journal.pone.0233147