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This article is original by Translational Medicine Network.
Please indicate the source for reprinting.
Author: Ashley Guide: A recent study uses a new brain activity model to explore an astonishing burst of activity in the human brain that has never been examined
.
This new model provides us with a better lens through which we can observe the brain and see more clearly what happens under normal and abnormal conditions
.
Research has identified brief intermittent bursts of co-fluctuations of signals within the brain, called events, and have shown that events drive functional connectivity
.
Computational neuroscientists Maria Pope, Richard Betzel, and Olaf Sporns of Indiana University are using a new model of brain activity to explore an astonishing burst of activity in the human brain that has never been examined
.
These outbreaks may have the potential to be biomarkers for brain diseases and conditions, such as depression, schizophrenia, dementia, and hyperactivity
.
When analyzing human neuroimaging data, the Indiana University research team found that short pulses of continuous "events" are formed in the brain, and they are always happening regardless of the activity or state of the brain
.
Researchers found that during a 10-minute brain scan, these events occurred approximately 10 to 20 times, each lasting only a few seconds
.
Robert H.
Shaffer Chair, Olaf Sporns, Distinguished Professor and Robert H.
Shaffer Chair, Olaf Sporns, of the Department of Psychology and Brain Science, College of Arts and Sciences, Indiana University, Bloomington, said: “What people don’t see is that the communication between brain regions is interrupted by these short moments.
Now, in just a few seconds, a lot of things happened
.
"Now that we see them, we focus on these moments to understand how specific brain regions connect and talk to each other during these events
.
"
"To begin investigating how these mysterious events work, the research team built a computational model
.
Under the leadership of Maria Pope, a graduate student in the Sporns laboratory and a dual doctoral candidate in neuroscience and informatics, the team used neuroimaging data from the human brain.
A model was built and its connections were replicated
.
Then, the model was simulated to a state similar to a resting brain to generate synthetic MRI signals, and mathematical equations were used to reproduce neuronal activity
.
The model showed the recordings of the human brain I saw a similar outbreak
.
On November 16th, the Proceedings of the National Academy of Sciences (PNAS) published a paper entitled "Modular origins of high-amplitude cofluctuations in fine-scale functional connectivity dynamics", which outlined the The model and how it compares with the real brain
.
Pope said: "This model tells us that these events are guided by the structural network of the brain, and they are related to the physical structure of the brain
.
"More specifically, these events originate in neuron clusters and brain regions.
These neuron clusters are closely connected to brain regions and emit light together in an instant
.
Sporns compares this pattern to an orchestra playing a piece of music
.
Sporns said:" Sometimes orchestras get together and have a theme
.
They don't just play a note for 10 minutes
.
In some brief moments, coordination activities dominate, while at other times, it may be much less.
This coordination ups and downs are also what we see in the brain, and our model can replicate it
.
Clusters of brain regions combine in different ways
.
This is not just a pattern, but multiple variations of a theme
.
"Sporns believes that the results of the new model may change the rules of the game
.
Sporns said: "Functional connectivity as a potential biomarker of brain diseases has always been the focus of research and is associated with depression, schizophrenia, dementia, and ADHD
.
Researchers have been trying to use brain simulations in clinical applications to simulate lesions or to model for many years
.
This new model provides us with a better lens through which we can observe the brain and see more clearly what happens under normal and abnormal conditions
.
"Researchers are now delving into why the human brain uses these short-lived activities
.
"
Pope said: "Maybe the brain develops this activity because it is beneficial
.
Some things about the event structure may be useful to the brain.
For example, many types of network systems have to occasionally update or restart the system to obtain some globally useful information and transmit it to the rest of the system
.
"The answers to these questions may not only be meaningful for understanding the brain, but also for the study of neural networks and artificial intelligence
.
Betzel, professor of psychology and brain science in the Department of Arts and Sciences, said: "The structure and function are mapped more clearly at the individual level.
The atlas may have an impact on how we diagnose neurological diseases and lead to personalized treatment and intervention
.
"Reference material: https://medicalxpress.
com/news/2021-11-neuroscientists-explore-brain-events-injuries.
html Note: This article is intended to introduce medical research progress and cannot be used as a reference for treatment plans
.
If you need health guidance , Please go to a regular hospital for treatment
.
Recommendations·Activities New diagnostic technology clinical application Salon hot·Articles Vaccine R&D [Nature] Pharmaceutical giant Sanofi and others are leading the development of protein vaccines.
The era of protein-based COVID-19 vaccines may be coming soon! Cancer Treatment [Nature Sub-Journal] Large-scale study of 480,000 people: In the face of extremely lethal liver cancer and chronic liver disease, scientists have confirmed that whole grains and dietary fiber can greatly reduce the risk of death! Cancer treatment [eLife] Infrared fingerprints can help detect Cancer? The future is bright! Medical research [Science Sub-Journal] Cupping + New Coronary DNA Vaccine = Immune Response × 100, Chinese scientists combined ancient and modern medicine and invented a new transfection method! New Coronavirus [Science Breakthrough] Nobel Prize Female scientists develop new system tools, focusing on a rarely noticed mutation in Delta, revealing why Delta is so contagious? Gene sequencing [BMJ] benefits all mankind! The pain of rare disease diagnosis will become history, whole genome sequencing is a medical development The inevitable trend of genetic disease treatment [Science] The era of RNA drugs has arrived, and the future is bright! Soon it may bring good news to patients with rarer genetic diseases.
Cancer treatment [AACR sub-Journal] New insights! Gastric cancer atlas brings new ideas Treatment strategy!
Please indicate the source for reprinting.
Author: Ashley Guide: A recent study uses a new brain activity model to explore an astonishing burst of activity in the human brain that has never been examined
.
This new model provides us with a better lens through which we can observe the brain and see more clearly what happens under normal and abnormal conditions
.
Research has identified brief intermittent bursts of co-fluctuations of signals within the brain, called events, and have shown that events drive functional connectivity
.
Computational neuroscientists Maria Pope, Richard Betzel, and Olaf Sporns of Indiana University are using a new model of brain activity to explore an astonishing burst of activity in the human brain that has never been examined
.
These outbreaks may have the potential to be biomarkers for brain diseases and conditions, such as depression, schizophrenia, dementia, and hyperactivity
.
When analyzing human neuroimaging data, the Indiana University research team found that short pulses of continuous "events" are formed in the brain, and they are always happening regardless of the activity or state of the brain
.
Researchers found that during a 10-minute brain scan, these events occurred approximately 10 to 20 times, each lasting only a few seconds
.
Robert H.
Shaffer Chair, Olaf Sporns, Distinguished Professor and Robert H.
Shaffer Chair, Olaf Sporns, of the Department of Psychology and Brain Science, College of Arts and Sciences, Indiana University, Bloomington, said: “What people don’t see is that the communication between brain regions is interrupted by these short moments.
Now, in just a few seconds, a lot of things happened
.
"Now that we see them, we focus on these moments to understand how specific brain regions connect and talk to each other during these events
.
"
"To begin investigating how these mysterious events work, the research team built a computational model
.
Under the leadership of Maria Pope, a graduate student in the Sporns laboratory and a dual doctoral candidate in neuroscience and informatics, the team used neuroimaging data from the human brain.
A model was built and its connections were replicated
.
Then, the model was simulated to a state similar to a resting brain to generate synthetic MRI signals, and mathematical equations were used to reproduce neuronal activity
.
The model showed the recordings of the human brain I saw a similar outbreak
.
On November 16th, the Proceedings of the National Academy of Sciences (PNAS) published a paper entitled "Modular origins of high-amplitude cofluctuations in fine-scale functional connectivity dynamics", which outlined the The model and how it compares with the real brain
.
Pope said: "This model tells us that these events are guided by the structural network of the brain, and they are related to the physical structure of the brain
.
"More specifically, these events originate in neuron clusters and brain regions.
These neuron clusters are closely connected to brain regions and emit light together in an instant
.
Sporns compares this pattern to an orchestra playing a piece of music
.
Sporns said:" Sometimes orchestras get together and have a theme
.
They don't just play a note for 10 minutes
.
In some brief moments, coordination activities dominate, while at other times, it may be much less.
This coordination ups and downs are also what we see in the brain, and our model can replicate it
.
Clusters of brain regions combine in different ways
.
This is not just a pattern, but multiple variations of a theme
.
"Sporns believes that the results of the new model may change the rules of the game
.
Sporns said: "Functional connectivity as a potential biomarker of brain diseases has always been the focus of research and is associated with depression, schizophrenia, dementia, and ADHD
.
Researchers have been trying to use brain simulations in clinical applications to simulate lesions or to model for many years
.
This new model provides us with a better lens through which we can observe the brain and see more clearly what happens under normal and abnormal conditions
.
"Researchers are now delving into why the human brain uses these short-lived activities
.
"
Pope said: "Maybe the brain develops this activity because it is beneficial
.
Some things about the event structure may be useful to the brain.
For example, many types of network systems have to occasionally update or restart the system to obtain some globally useful information and transmit it to the rest of the system
.
"The answers to these questions may not only be meaningful for understanding the brain, but also for the study of neural networks and artificial intelligence
.
Betzel, professor of psychology and brain science in the Department of Arts and Sciences, said: "The structure and function are mapped more clearly at the individual level.
The atlas may have an impact on how we diagnose neurological diseases and lead to personalized treatment and intervention
.
"Reference material: https://medicalxpress.
com/news/2021-11-neuroscientists-explore-brain-events-injuries.
html Note: This article is intended to introduce medical research progress and cannot be used as a reference for treatment plans
.
If you need health guidance , Please go to a regular hospital for treatment
.
Recommendations·Activities New diagnostic technology clinical application Salon hot·Articles Vaccine R&D [Nature] Pharmaceutical giant Sanofi and others are leading the development of protein vaccines.
The era of protein-based COVID-19 vaccines may be coming soon! Cancer Treatment [Nature Sub-Journal] Large-scale study of 480,000 people: In the face of extremely lethal liver cancer and chronic liver disease, scientists have confirmed that whole grains and dietary fiber can greatly reduce the risk of death! Cancer treatment [eLife] Infrared fingerprints can help detect Cancer? The future is bright! Medical research [Science Sub-Journal] Cupping + New Coronary DNA Vaccine = Immune Response × 100, Chinese scientists combined ancient and modern medicine and invented a new transfection method! New Coronavirus [Science Breakthrough] Nobel Prize Female scientists develop new system tools, focusing on a rarely noticed mutation in Delta, revealing why Delta is so contagious? Gene sequencing [BMJ] benefits all mankind! The pain of rare disease diagnosis will become history, whole genome sequencing is a medical development The inevitable trend of genetic disease treatment [Science] The era of RNA drugs has arrived, and the future is bright! Soon it may bring good news to patients with rarer genetic diseases.
Cancer treatment [AACR sub-Journal] New insights! Gastric cancer atlas brings new ideas Treatment strategy!
