PNAS: How do ultramicrobacteria in the environment adapt to life in the human body

The microorganisms that live in our mouths, collectively referred to as the oral microbiome, affect our overall health in many ways, but we still don't fully understand them

Among the various bacterial species living in our mouths, there is a group that belongs to the phylum Radiation Candidate (CPR)

To better understand these elusive bacteria, Dr.

Scientists have found TM7 in many different environments, including soil, groundwater, and the corpses of other mammals

Dr.

The researchers hypothesized that the acquisition of ADS by TM7 is an evolutionary advantage that helps them adapt and survive in the human mouth

In the end, experiments showed that due to the presence of ADS, TM7x can survive longer in the experimental environment than without arginine

"Most of the current research on CPR bacteria is based on culture-independent genomic methods

"The production of ammonia through TM7-encoded advertising raises the pH in the human oral microenvironment, which raises an interesting question about the role of TM7 in the development of dental caries," said Dr.

This study also adds more and more evidence that TM7 bacteria may have a greater protective effect on oral health than the researchers initially believed

Dr.

"This is why it is so important to establish a bacterial model system, not only to better understand the unique life>

Article title

Acquisition of Arginine Deiminase System benefits epiparasitic Saccharibacteria and its host bacteria in mammalian niche environment