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Positive Phase 2 Clinical Results of LAG-3 Therapy for Non-Small Cell Lung Cancer

 Last Update: 2022-04-22
 Source: Internet
 Author: User

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Today, Immutep announced that its LAG-3 fusion protein eftilagimod alpha (efti, also known as IMP321), in combination with Merck & Co.

LAG-3 protein can regulate the signaling pathway of T lymphocytes and antigen presenting cells (APCs), and plays an important role in adaptive immune response

Image source: Immutep official website

Eftilagimod alpha is a soluble LAG-3 fusion protein

In this part of the clinical trial, 36 advanced patients were treated

The test results show:

73.

73% of patients were still alive 6 months after treatment

The disease control rate was 36.

The objective response rate was 5.

Median overall survival has not been reached

Image source: Reference [1]

Dr.

References:

[1] Immutep's efti in combination with MSD's pembrolizumab shows encouraging antitumor activity in difficult to treat 2nd line metastatic lung cancer patients.

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