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(4) Cyclohexanol catalytic amination method
In the presence of hydrogen, with Rb/Al 2 O 3 as a catalyst, the reaction temperature is controlled to about 150°C, cyclohexanol is heated in the autoclave, and then ammonia is introduced to produce cyclohexylamine and bicyclohexylamine, which are refined Two products of cyclohexamine and dicyclohexamine were obtained
(5) Cyclohexanone catalytic ammonolysis method
Must be carried out in the presence of hydrogen
The main reaction of this route is:
The side effects are:
Put 98g (1mol) of cyclohexanone into the autoclave, heat up to 353K, press in 51g (3mol) of ammonia, pass in hydrogen, adjust the pressure to above 8.
(6) Cyclohexanone oxime catalyzed amination
Chen Zhixin and others used cyclohexanone oxime as a raw material and Raney Ni as a catalyst.
① Prepare fresh Raney nickel catalyst, dissolve 2g Ni-Al alloy in 100mL sodium hydroxide aqueous solution containing 10g sodium hydroxide in batches until no more bubbles are generated
②In a 500 mL autoclave, 80 mL (62.
③After the reaction, cool to room temperature naturally, slowly release hydrogen, open the autoclave, and filter the above reaction product with nitrogen pressure to obtain filtrate A and filter cake; the filter cake is Raney Ni catalyst, which can be recycled
The 80-82°C distillate is collected as cyclohexane, which can be recovered and recycled
The method for synthesizing cyclohexamine has mild reaction conditions, low production cost, simple equipment, easy operation and industrialization
(7) Nitrocyclohexane reduction method
[Technical index] HG/T2816-1996 industrial cyclohexamine
[Application] Cyclohexamine is strongly alkaline
It is generally used as a pH regulator for boiler feedwater in water treatment
In addition, the synthesis can also be used desulfurizing agent, corrosion inhibitor, a vulcanization accelerator, emulsifiers, antistatic agents and the like