Preparation of N, O ligand chelating resin

Amino carboxylic acids are the most important series of such resins, and iminodiacetate (IDA) resins are the most important commercial chelating resins

① Introducing ligands such as styrene iminodiacetic acid type chelating resins on the polymer carrier through polymer reaction is prepared by introducing functional groups into the polystyrene matrix obtained by styrene-divinylbenzene copolymerization

Synthesis of iminodiacetic acid resin:

Synthesis of O-hydroxybenzyl iminodiacetic acid:

②Polymerization reaction of vinyl monomers containing amino carboxylic acid First synthesize the vinyl monomers containing amino carboxylic acid, and then carry out the polymerization reaction

In addition, styrene-based IDA resins can be synthesized from chloromethylated intermediates or aminated products (weakly basic anion exchange resins with primary amino groups) as starting materials

Hydrophobic chloromethyl cross-linked polystyrene is difficult to react with water-soluble nucleophilic amino carboxylic acid, so it is impossible to use such reagents for amination and directly obtain IDA resin

Acrylic and other polycondensation polyamine resins and meta- or para-phenylene diamines can also be used to prepare IDA resins

When preparing IDA resin by the above-mentioned various methods, the chlorocarboxylic acid used can be β-chloropropionic acid, γ-chlorobutyric acid, etc.

There are other methods for preparing imine carboxylic acid resins, but styrene-based IDA is still the most important

8-Hydroxyquinoline resin is also N, O coordination and integration agent, and there are many synthetic methods

Firstly, 8-hydroxyquinoline is chloromethylated, and then reacted with primary amine resin at 100°C for 10 hours to obtain spherical chelating resin:

Using 5-chloromethyl-8 quinoline, under the catalysis of SnCl ₄ and macroporous cross-linked polystyrene for Friedel-Crafts reaction, 8-hydroxyquinoline resin can also be obtained

Schiff base is also a large class of N, O chelating resins

The structure of the chelate formed with Cu ²⁺ is:

The structure of the Schiff base resin synthesized by the condensation of 2,6-diamino-p-cresol and glyoxal is

The chelate structure formed with Cu ²⁺ is similar to the above integrant

Related link: Condensation type anion exchange resin