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    Home > Active Ingredient News > Drugs Articles > Principle and cleaning method of multi effect distilled water machine

    Principle and cleaning method of multi effect distilled water machine

    • Last Update: 2017-10-25
    • Source: Internet
    • Author: User
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    Working principle of multi effect distilled water machine: multi effect distilled water machine is a steam heated distilled water production equipment with deionized water as raw water The distilled water produced by the equipment has stable quality, high purity and no pyrogen At present, Zui is the key equipment of widely used WFI preparation system The multi effect distilled water machine adopts high temperature and high pressure operation to ensure stable production of non pyrogenic injection water The distilled water produced by the multi effect distilled water machine completely meets the requirements of water for injection in the current USP, EP, JP and CP Cleaning method analysis of multi effect distilled water machine: there are two kinds of scale produced in multi effect distilled water machine, one is boiler scale, the other is silica scale Different cleaning agents should be used for cleaning: 1 For boiler scale, sulfamic acid (nh2so2oh) can be used When using, deionized water is used to prepare a cleaning solution with a concentration of 1% Its pH value is between 1 and 2, and it is heated to about 60 ℃ Phosphoric acid (H3PO4) can also be used to prepare a 2% concentration cleaning solution with deionized water and heat it to about 65 ℃ 2 For silica scale, ammonium difluoride (NH4HF2) can be used to prepare a 1.5% concentration solution with deionized water and heat it to 50 ℃ ~ 60 ℃ Sodium hydroxide + anionic active agent can also be used to prepare a cleaning solution with a concentration of 10% and heated to about 60 ℃ When the above two kinds of scale are removed by chemical cleaning method, many users of multi effect distilled water machine also use the general stainless steel cleaning agent which is sold in the market, with good effect and convenient use After cleaning with acid solution, neutralization solution is generally required The neutralization solution was prepared by adding 0.5% sodium bicarbonate (hahco3) and 0.1% anionic surfactant into deionized water  
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