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    Home > Active Ingredient News > Drugs Articles > Principle and method of dust particle counter to detect whether the filter leaks

    Principle and method of dust particle counter to detect whether the filter leaks

    • Last Update: 2018-12-03
    • Source: Internet
    • Author: User
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    Dust particle counter detects whether the filter leaks, mainly to avoid air filter leakage and affect the whole production It is mainly to check whether the suspended particles of each point are beyond the range required by the clean area If so, there is leakage, which needs to be plugged or replaced This is also a relatively simple and accurate operation method After the filter is installed or replaced, the installation connection of the filter must be checked for leakage to ensure that the cleanliness of the clean room meets the requirements The dust particle counter is mainly used to detect the leakage of the filter based on the principle of light scattering During the counting and measurement, the photomultiplier tube is used to receive the light reflected by the dust particle to measure its size and quantity, and to analyze the accumulation and digital display Before the experiment, the temperature should be controlled at 18-26 ℃; the relative humidity should be controlled at 45-65% There shall be no more than 2 indoor testers For rooms with different indoor cleanliness, the static pressure difference is ≥ 5pa, and the static pressure difference between clean area and non clean area is ≥ 10Pa; for rooms with large amount of dust produced in the process, the relative negative pressure should be maintained with other rooms With these objective conditions, the next step is to carry out the actual steps: 1 The dust particle counter is sterilized with water for injection and 75% alcohol, and then transmitted to the clean area through ultraviolet irradiation for 30 minutes 2 Place the dust particle counter horizontally on the table The measuring plastic pipe port is connected to the filter nozzle 3 Turn on the power After the instrument performs self inspection and selection, pull the measuring plastic pipe off the rear panel The port is placed where it needs to be measured 4 During the detection, the sampling head is 2-4cm away from the filter, scan slowly along the inner frame and the middle of the filter, test at least 5 points of each filter, and observe the displayed data After the test, connect the sampling plastic pipe port to the rear panel of the dust particle counter for self inspection Then turn off the power Dust particle counter was used to measure the result of filter in 100 grade clean area Through the above measurement, we can see whether the filter has leakage If it needs to be plugged or replaced, the filter must be retested after repair or replacement The recommended long time interval is 24 months DOP leakage detection shall be carried out after HEPA installation or replacement When the environmental monitoring shows that the air quality deteriorates, or the sterility test of the product fails, or the simulated filling test of the culture medium fails, the leakage can be detected as part of the deviation investigation The filter to be tested also includes HEPA used for drying the tunnel and oven.
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