Product use and safety measures of 2-aminophenol-4-sulfonamide

2-aminophenol-4-sulfonamide (2-amino-l-phenol -4-sulfonylamide) , also known as o-aminophenol 4- sulfonamide, of the formula C _.
6 H _.
8 N ₂ O _.
3 S, molecular weight of 188.
20, the formula

1.
Product performance

This product is off-white or light brown feather-like crystals; melting point is 194～196℃; slightly soluble in water, soluble in acid and alkali, the color will gradually darken when placed in the air; toxic
.

2.
Production principle

O-nitrochlorobenzene is chlorosulfonated with chlorosulfonic acid to obtain 4-chlorosulfonyl-2-nitrochlorobenzene, which is then ammoniated to obtain 4-sulfonamido-2-nitrochlorobenzene, which is then hydrolyzed into caustic soda 4-sulfonamido-2-nitrophenol sodium salt is acidified with hydrochloric acid and then reduced with iron powder to obtain 2-aminophenol-4-sulfonamide
.

3.
Process flow

4.
Technical formula (kg/t

5.
Main equipment

Chlorosulfonation reactor, ammoniation reactor, filter, storage tank, reduction reactor, drying box
.

6.
Production process

(1) Add 762kg of chlorosulfonic acid into the chlorosulfonation kettle, and add 154kg of molten o-nitrochlorobenzene within 1 hour at a temperature lower than 60°C
.

(2) Add water and 25% ammonia to the ammoniation reactor, and add 2-nitrochlorobenzene-4-sulfonyl chloride filter cake at 15-20°C for 1 hour
.

(3) Add water to the reduction pot, add iron powder and industrial hydrochloric acid under stirring
.

7.
Product Standard

8.
Product use

Dye intermediates, mainly used to produce diazo components of neutral dyes
.

9.
Safety measures

(1) When using o-chloronitrobenzene, chlorosulfonic acid and other toxic or corrosive raw materials in production, the reaction equipment should be sealed to prevent leakage
.

(2) This product is toxic.
It is packed in a cardboard drum lined with a plastic bag and stored in a cool, ventilated place
.