Product uses and safety measures of 2-chloro-4-nitroaniline

2-chloro-4-nitroaniline (2-chloro-4-nitroaniline) is also known as o-chloro- p -nitroaniline, 4-amino-3-chloronitrobenzene (4-amino-3-chloronitrobenzene), the molecular formula is C ₆ H ₅ CIN ₂ O ₂ , the molecular weight is 172.
58, and the structural formula is

1.
Product performance

Yellow needle-like crystals, melting point 107～109℃; soluble in ethanol , ether , carbon disulfide and benzene, slightly soluble in water and 50% acid, insoluble in crude gasoline; toxic
.

2.
Production principle

After p-nitroaniline is salted with hydrochloric acid, it is chlorinated with sodium hypochlorite to obtain the product
.

3.
Process flow

4.
Technical formula (kg/t)

5.
Main equipment

Reaction pot, filter press, storage tank, dryer
.

6.
Production process

Add 450L of water, 1120kg of 30% hydrochloric acid to the reaction pot, increase the temperature to 50°C, add 185.
6kg of p-nitroaniline, and stir for 20min to dissolve
.

7.
Product Standard

8.
Quality inspection

Assay: Accurately weigh about 2.
5g sample, place it in a 400mL clean drying cup, add 30mL hydrochloric acid and 100mL distilled water, heat and dissolve on an electric stove, add distilled water to dilute to a total of 300mL
.

In the formula: c——molar concentration of sodium nitrite standard solution, mol/L;

V——The volume of sodium nitrite standard solution consumed by the sample, mL;

V ₁ ——The volume of sodium nitrite standard solution consumed in the blank experiment, mL;

G——The mass of the sample, g
.

9.
Product use

Used as dyes, pigments and pharmaceutical intermediates, such as the synthesis of Disperse Red B, Silver Bead R, and Schistosomiasis-67 paste
.

10.
Security measures

(1) The raw material is highly toxic to nitroaniline, and the maximum allowable concentration in the air is 0.
0001%
.

(2) The products are packed in iron drums or plastic bags and stored in a cool, dry place
.