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    Home > Active Ingredient News > Drugs Articles > Production and sales growth price volatility Vitamin E outlook remains promising

    Production and sales growth price volatility Vitamin E outlook remains promising

    • Last Update: 2021-02-09
    • Source: Internet
    • Author: User
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    In recent years, China's vitamin E (VE) production and export volume continue to climb, but the market price fluctuates up and down, and a larger range, attracting attention.production is relatively concentrated
    VE is divided into natural products and synthetics, of which natural VE production is only about 20%. Over the years, the United States is the world's largest producer of synthetic VE, production accounted for about 40% of the world's TOTAL VE production, other large producers Germany, Switzerland, Japan, France and so on. At present, the world VE production capacity of about 140,000 tons, production giants have DSM, BASF and other companies. China has now become the world's largest VE production country, annual production capacity of more than 100,000 tons, annual output of more than 70,000 tons.
    as of June 20, 2017, there were 375 approval numbers for vitamin E production nationwide. Among them, the raw materials production approval number 7, the main production enterprises are Zhejiang Pharmaceutical Co., Ltd. Xinchang Pharmaceutical Factory, Chongqing Southwest Synthetic Pharmaceutical Co., Ltd., Zhejiang Xinhe Cheng Co., Ltd., Wuxi Fuyue Pharmaceutical Co., Ltd., Shaanxi West Yue Pharmaceutical Co., Ltd.
    VE synthesis process needs to go through more than 20 steps of reaction, many reaction steps, long route, high technical requirements, most of its production equipment for special equipment, high technical barriers. Therefore, for a long time, only a few enterprises in the world produce VE, mainly the Netherlands DSM, Basf and China's Zhejiang Pharmaceutical, New Synthesis and other four enterprises, these companies together account for about 90% of the world's production capacity, forming an oligopoly pattern.
    , DSM of the Netherlands (with an annual capacity of 25,000 tons) and BASF of Germany (20,000 tons) account for about 50% of the production capacity, and Zhejiang Pharmaceuticals (22,000 tons, the largest producer in the country and the world's second largest producer) and Xin and Cheng (15,000 tons) account for about 40% of the capacity. All four enterprises are based on methylphenol and other raw materials, with strong technical barriers. Over the years, in addition to Xin and Cheng and Zhejiang medicine, there are southwest synthesis and other enterprises also produce VE raw materials, and recently some enterprises have entered the production ranks of synthetic VE.
    , according to statistics on the CFDA website, as of the end of June 2017, several companies nationwide had obtained VE's 26 GMP certifications. Among them, more GMP certificate enterprises are: Zhejiang Xinhe Cheng shares (4), Zhejiang Pharmaceutical Xinchang Pharmaceutical Factory (3), Southwest Synthetic Pharmaceuticals (3); Jinliyuan Pharmaceuticals and Shaanxi Xiyue Pharmaceuticals won 2 respectively, while Zhejiang Jutai Pharmaceuticals, Anhui Great Oriental Pharmaceuticals, Zhejiang Nojin Pharmaceuticals, Northeast Pharmaceuticals, Zhejiang Anlikang Pharmaceuticals and Huazhong Pharmaceutical Co., Ltd. received 1 each.prices fluctuate up and down
    In recent years, China's VE export growth momentum is strong, export volume accounted for 80% to 90% of global trade volume, the main export destinations for North America, Western Europe and Asia and other places. Over the years, the United States is China's VE's largest exporter, exports of more than 10,000 tons, accounting for more than a fourth of the total export volume. Germany is also China's VE exports, export volume also reached 10,000 tons, accounting for nearly a/4.
    years, the international market VE prices fluctuate up and down, and the range is large. Average export prices in 2015 were only 46% of 2011, less than half of them, a record low. In that year, the market price of domestic VE also fell all the way. At the beginning of January 2015, the average price of domestic feed-grade VE (content 50%) was RMB63,100 per ton, rmb 43,520 in October 2015, and by the end of December, the average price quoted by manufacturers was RMB41,000 per tonne, down 35.36%, with some dealers trading at RMB39,000 per tonne. Due to the low market price of VE, China's production enterprises generally operating difficulties.
    2016, VE market prices began to stabilize and rebound. Ve prices have been rising strongly since the end of February 2016. In mid-April 2016, the price of VE in the domestic market reached RMB59,600 per tonne, an increase of about 44% from the beginning of the year. During the year, the price of VE in the international market is also rising, and the price of VE for our exports has been rising, from more than $8 per kilogram in 2015 to about $14 per kilogram.
    VE export prices rose sharply, manufacturers are very profitable, enterprises have opened full horsepower production. Other enterprises see this huge profit, also joined the ranks of production, VE production in the short term increased faster, the market supply and demand balance was broken. In 2017, VE's market price began to decline. In mid-June 2017, china's market feed-grade VE prices are also at a low level, some manufacturers have quoted around 4000 yuan per ton.outlook is still optimistic
    according to analysis, the future domestic and foreign VE market demand will continue to grow, the outlook is good, the main reasons are three:
    First, the market application is wide-ranging. Since the 1977 edition of the Chinese Pharmacopoeia, it has been included in previous editions. In addition, it is included in the U.S. Pharmacopeia USP40, british Pharmacopeia BP2017, Japanese Pharmacopeia JP17, Korean Pharmacopeia 10th Edition, and European Pharmacopeia EP9.0. VE is also an early entry into China's over-the-counter drug varieties, according to the CFDA website statistics show that as of June 20, 2017, there are 61 over-the-counter drugs involving VE, both unilateral preparations, but also many compound preparations.
    VE is also one of the products of multivitamins, such as 21 gold vitamins, good deposits, and kimschelcon. These products have entered thousands of households, the country's annual sales of tens of billions of yuan, is expected in the future in the 1.3 billion people (including more than 200 million elderly) in the Chinese market, sales will continue to rise.
    in the beauty, VE on the skin of the beauty maintenance effect is certain, foreign major washing companies of high-grade skin care and beauty products will be VE as an important additive. In recent years, more and more domestic washing companies have also introduced VE-containing skin care and beauty products to the market, which has great potential.
    second is that there is progress in clinical research. In recent years, experts and scholars at home and abroad have carried out extensive and in-depth research on the physiological and pharmacological effects of VE, and found that VE can participate in the body's multi-faceted metabolic process, the role is extensive and complex, with many and ginseng-like role, clinical value is increasingly important, many uses, has been involved in internal, external, women, children, infection, skin, radiation and other departments, become one of the modern popular drugs.
    is the demand for feed additives. Currently, about 80% of VE is used as a feed additive worldwide, e.g. the appropriate content of VE per kilogram of chicken feed is 5 I Units. 20% of VE is used in medicine and food. China's production of VE is mainly used for feed addition, BASF and DSM mainly produce high-end pharmaceutical food grade VE. With the increasing global population, the world economy is gradually rising, feed production growth is significant, the current annual global feed production has reached about 1 billion tons, it is expected that the future global feed production will maintain a stable growth of about 2%, the future VE demand will continue to rise.
    the development of China's aquaculture industry led to a sharp increase in the production of various feeds year after year. According to rough statistics, in the past 10 years, the national average annual increase of about 8 million tons of feed, now about 4000 mixed feed production enterprises, annual output of about 200 million tons of feed, accounting for about 1/5 of the world. With the continuous improvement of people's living standards in China, the aquaculture industry will continue to develop steadily in the next few years, it is expected that by 2020, China's annual feed production will reach 240 million tons, accounting for about 1/4 of the global total, feed additives demand for VE will continue to grow. (Medical Economics)
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