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    Home > Food News > Food Articles > Professor Chen Feng's team published an important paper on "nutrient regulation of iron deficiency anemia" in the top international food and nutrition journals

    Professor Chen Feng's team published an important paper on "nutrient regulation of iron deficiency anemia" in the top international food and nutrition journals

    • Last Update: 2022-04-15
    • Source: Internet
    • Author: User
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    Recently, the research group of Professor Chen Feng from the Institute for Advanced Study of Shenzhen University published a paper entitled "Prebiotic oligosaccharides regulate protein Prebiotic oligosaccharides enhance iron absorption via modulation of protein expression and gut microbiota in a dose-response manner in iron-deficient growing rats.
    The research was completed in cooperation with the Institute for Advanced Study of Shenzhen University and Southern Medical University

    .
    Professor Chen Feng from the Institute for Advanced Study of Shenzhen University and Professor Deng Hong from Southern Medical University are the co-corresponding authors, and Associate Researcher Chen Jiehua (Shenzhen University) is the first author

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    The Institute for Advanced Study of Shenzhen University is the first completion unit

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    Based on the iron-deficiency anemia problem that is currently seriously endangering the health of children and adolescents in China, the research was based on the iron-deficiency anemia rats in the growing phase to simulate anemia in children, and to explore the effects of fructooligosaccharides (FOS) and galactooligosaccharides (GOS) at different concentrations.
    Effects on intestinal iron absorption in rats (Figure 1)

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    The purpose of this study was to explore the mechanism of how GOS affects iron absorption in an iron-deficient growth rat model from the perspective of protein expression and gut microbiota, and to determine the optimal dose of GOS

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    In this study, iron-deficiency animal models were established by feeding young mice an iron-deficiency diet for 14 days

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    Iron-deficient rats were then provided with standard rat chow supplemented with 0%, 3%, 5%, 10% GOS, and 10% FOS for 21 days

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    The results showed that dietary supplementation of ≥5% GOS improved iron status in iron-deficient rats and significantly affected the expression of iron binding/transporters

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    Furthermore, the findings identify a dose-dependent modulation of the gut microbiota by GOS

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    This study is the first to provide evidence that GOS supplementation produces a dose-response relationship between iron absorption and intestinal flora in an established model, proving that GOS has a positive role in the regulation of iron absorption and utilization, and providing a reference for the selection of prebiotic additives

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    Project funding

    The above research work was supported by the National Natural Science Foundation of China (31601472), the Pearl River Innovation and Entrepreneurship Team (2019ZT08H476) and the Peacock Team (KQTD20180412181334790)
    .

    About the corresponding author

    Professor Chen Feng

    Academician of American Academy of Medical and Biological Engineering, Academician of International Eurasian Academy of Sciences

    Distinguished Professor and Doctoral Supervisor of Shenzhen University

    work experience:

    He is currently the Dean of Shenzhen University Institute for Advanced Study, Dean of Shenzhen University Food Industry Innovation and Development Research Institute, Director of Shenzhen Key Laboratory of Marine Microbiome Engineering, Honorary Professor of the University of Hong Kong, and Honorary Professor of the University of Queensland, Australia
    .
    He used to be a tenured chair professor of Peking University, deputy dean of the School of Engineering of Peking University, director of the Institute of Food and Bioresources Engineering of Peking University School of Engineering, chief scientist of biomass energy of the Advanced Innovation Center for Engineering Science and Emerging Technologies of Peking University, Singapore - Director of the Low Carbon Research Center of Peking University, tenured professor of the University of Hong Kong and Executive Dean of the School of Biological Sciences

    .

    Honors:

    "Outstanding Youth Research Award", "Outstanding Graduate Mentor Award", "France-Hong Kong Joint Research Award", "The First China Food Science and Technology Outstanding Young and Middle-aged Award" of the University of Hong Kong
    .
    In 2004, he was selected as a "Changjiang Scholar" by the Ministry of Education, in 2008, he was elected as an "Academician of the American Academy of Medical and Biological Engineering (AIMBE)", in 2010, he was awarded the "American Institute of Chemical Engineers Conference Award", and in 2011, he was selected as a "Royal Society of Chemistry (Royal Society of Chemistry (AIMBE)".
    In 2014, he was elected as an "Academician of the International Academy of Food Science (IAFoST)" and "Academician of the International Eurasian Academy of Sciences (IEAS)".
    In 2019, he was awarded the Outstanding Teochew Person of "Chaos Fighting the World" by the Federation of Hong Kong Teochew Associations Award, in 2020 won the "Chinese Overseas Contribution Award (First Prize)"

    .

    Research Interests:

    Mainly concentrated in the fields of microalgae biological resources and bioenergy, bioengineering and functional food
    .

    Academic Achievements:

    So far, 350 research papers and reviews (according to Google Scholar, more than 25,000 citations, H-Index 87), 5 monographs, and 31 US and Chinese patents have been published in international academic journals (SCI)
    .
    He has been invited to speak at international academic conferences many times, and has organized many international academic conferences

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    He was rated as the Global Highly Cited Scientist in 2017, the Chinese Highly Cited Scientist in 2018 and 2019, and the top 100,000 scientists in the world (currently ranked 17,430 in the world and 270 in China)

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    Associate Professor Deng Hong

    Associate professor and master tutor of the Department of Nutrition and Food Hygiene, School of Public Health, Southern Medical University
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    Main research directions: dietary nutrition and chronic diseases, N-nitroso compound pollution and its safety research

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