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Recently, the team of Professor Chen Hongmin from the Molecular Imaging Center of our hospital has made new progress in the research of magnetic resonance imaging probes and the application of early diagnosis of tumors.
Early diagnosis of malignant tumors is very important in clinical practice
Glioblastoma (GBM) is the most lethal primary brain malignancy with a median survival of only 14 months after diagnosis
In response to the clinical needs of clinical magnetic resonance contrast agents to reduce toxicity and enhance efficacy, this study developed manganese carbonized paramagnetic complexes (Mn@CCs) using food additives manganese gluconate and amino acids as precursors
In conclusion, using tumor -bearing mice as the research object, Mn@CCs have better imaging performance than the most widely used MRI contrast agents in orthotopic brain tumors and liver tumors, and can provide more reliable early diagnosis
This research work was completed under the guidance of Professor Chen Hongmin.
Full text link: https:// Imaging Center)