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The growth rate of chicken skeletal muscle directly determines the development of broiler industry, with the continuous improvement of chicken production, chicken has become the second largest meat consumer product in China, but China's local chicken breeds are in a weak position in the market, and it is still necessary to vigorously cultivate high-yield broilers
with independent intellectual property rights.
Traditional breeding methods are slow to cultivate, and it is urgent to accelerate the breeding process through molecular marker-assisted breeding, so mining the key regulators regulating the development of chicken skeletal muscle is the key to
molecular marker-assisted breeding.
with independent intellectual property rights.
Traditional breeding methods are slow to cultivate, and it is urgent to accelerate the breeding process through molecular marker-assisted breeding, so mining the key regulators regulating the development of chicken skeletal muscle is the key to
molecular marker-assisted breeding.
Recently, Professor Yin Huadong's team from the College of Animal Science and Technology of Sichuan Agricultural University published a report entitled "MyoG-enhanced circGPD2 regulates chicken skeletal muscle" in the internationally renowned journal "International Journal of Biological Macromolecules" (TOP Journal of CAS Region 1, IF=8.
025).
Research paper
by development by targeting miR-203a, (MyoG-induced circGPD2 regulates skeletal muscle development in chickens by targeting miR-203a).
In this paper, by constructing a comparative model of muscle growth, the specific expression mode of circGPD2 of circular RNA macromolecule is identified, and the function of circGPD2 in the development of chicken skeletal muscle and the upstream and downstream molecular regulation mechanism
of circGPD2 are clarified.
The results reveal that circGPD2 may play a key regulatory role in the growth and development of chicken skeletal muscle, provide new insights into the non-coding RNA regulatory mechanism of chicken skeletal muscle development, and provide an effective molecular target for molecular marker-assisted breeding to improve chicken productivity
.
025).
Research paper
by development by targeting miR-203a, (MyoG-induced circGPD2 regulates skeletal muscle development in chickens by targeting miR-203a).
In this paper, by constructing a comparative model of muscle growth, the specific expression mode of circGPD2 of circular RNA macromolecule is identified, and the function of circGPD2 in the development of chicken skeletal muscle and the upstream and downstream molecular regulation mechanism
of circGPD2 are clarified.
The results reveal that circGPD2 may play a key regulatory role in the growth and development of chicken skeletal muscle, provide new insights into the non-coding RNA regulatory mechanism of chicken skeletal muscle development, and provide an effective molecular target for molecular marker-assisted breeding to improve chicken productivity
.
Shen Xiaoxu, a 2020 doctoral student in animal genetics and breeding, is the first author of the paper, and Professor Yin Huadong is the corresponding author of the paper, and this research was funded
by the Applied Basic Project of Sichuan Science and Technology Department.
by the Applied Basic Project of Sichuan Science and Technology Department.
