Propynol (PA) physicochemical properties and preparation method

Propynol (PA)

[Structural formula]

CH≡C-CH ₂ OH

[Physical and chemical properties] This product is a colorless, volatile and pungent odor liquid

[Preparation]

(1) Recovery from the by-products of butynediol production by acetylene and formaldehyde high pressure method

Compress the acetylene content of 80%-90% to 0.

(2) Synthesized from "DD Mixture"

①a-1,3 Dichloropropylene extraction

"DD Mixture" is fractionally distilled to collect the fraction from 104 to 105°C, which is a-1,3 dichloropropene.

a-1,3 Chloropropene-2-ol preparation Put normal water into a 500mL three-necked flask, Na ₂ CO ₃ (or pre-prepared 10% Na ₂ CO ₃ ), stir and dissolve, add a-1,3 dichloropropene, The temperature is raised to 84～90℃ and the reaction is refluxed for 2h, cooled and neutralized with hydrochloric acid to a pH of 6～7, the reaction liquid is fractionated, 97～100℃ azeotrope is collected, and about 30g of oil layer is separated

③Preparation of propynol Add 46.

The use of "DD mixture" to synthesize propynol has convenient sources of raw materials, low price, simple technological process, and suitable for industrialization.

(3) Use glycerin by-product 2,3-difluoropropene to produce

It includes two stages: the acylation stage and the hydrolysis stage of 2-chloroallyl alcohol acetate

Related links: Technical indicators and applications of 2-mercaptobenzothiazole (MBT)