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At present, the most similar to the new coronavirus genome sequence is RaTG13 isolated from the chrysanthemum bat .
The Qian Wenfeng research group of the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences proposed a new traceability strategy-to speculate the historical host of the new coronavirus by identifying the spectral characteristics of the more than 500 mutations of the new coronavirus
After establishing the theoretical basis of this strategy, the authors constructed the evolutionary tree of SARS virus, Middle East respiratory syndrome virus, new coronavirus and 16 related coronaviruses
In order to speculate on the evolutionary history of the new coronavirus, the authors conducted a principal component analysis of the mutation characteristics of the new coronavirus during this period, and found that the mutation characteristics accumulated by the new coronavirus before the outbreak and the cell environment of wild bats (especially chrysanthemum bats) Highly consistent, which provides open, transparent and empirical data support for the natural origin of the new coronavirus
These findings in 2021 Nian 8 Yue 30 published in the May online The Innovation Journal ( DOI: 10.
