Questions about hydrophobic and hydrophobicity of amino acid sequences.

ask:

amino acids that make up the
antigen
are hydrophobic or hydrophobic? Why? And are the amino acids that make up the signal peptide hydrophobic or hydrophobic? Why? Please teach the master, thank you very much!
: The signal peptide sequence is in the range of 10-40 amino acid residues, the part of which has a length of 10-15 amino acids -based peptide chain consisting of highly hydrophobic amino acids. In general
protein
difficult to pass through the lipid membrane, but signal peptides can guide it through the membrane to a specific location.
amino acids that make up the antigen's surface are not necessarily hydrophobic. Take a look at this passage to see clearly:
the antigenicity profile methods are on the assumption that specific physicochemical profiles of the sequences side chains, invariably corresponds with immunodominant regions of the protein. Different groups have used different scales to define the antigenic potential profile along protein sequence e.g. inverted hydrophobicity scales, scales of turns, Flexibility scales etc. The algorithms are mainly available in the form of commercial (PeptideStructure and PepPlot of GCG, Protean module of
DNA
star) or freeware packages (EMBOSS, ProWin) etc.
Good luck!.