[quick news] on June 28, 2019, the "volume purchase" of drugs led to the "high platform diving" of some drug prices. Some drug prices dropped from more than 300 yuan to more than 10 yuan

Some drug prices have been driven by "volume purchase" Some drug prices have dropped from more than 300 yuan to more than 10 yuan in Beijing, Shanghai, Tianjin, Chongqing, and 11 cities in Shenyang, Dalian, Xiamen, Guangzhou, Shenzhen, Chengdu and Xi'an jointly launched national drug centralized purchase and use pilot projects, which have been officially launched for 3 months Through volume purchase, the average decline of 25 selected drugs was 52%, the maximum decline was more than 90%, and the price reduction effect was significant Among the 25 varieties of drugs purchased in this centralized purchase, the main treatment is hepatitis, lung cancer, leukaemia, hypertension and other diseases, three of which are original research drugs, and the remaining 22 are generic drugs that pass the consistency evaluation of quality and efficacy Taking the original research drug as an example, "gefitinib tablet" from AstraZeneca, a foreign-funded pharmaceutical enterprise, was selected at a price of 547 yuan, down 76% compared with 2280 yuan In the case of generic drugs, "entecavir dispersible tablets", 311.87 yuan before price adjustment, 17.36 yuan after price adjustment, a drop of 94% Http://www.xinhuanet.com/fortune/2019-06/28/c_.htm "China Weather 24 solar term research institute" was established in Beijing on June 27 The "China Weather 24 solar term research institute" (hereinafter referred to as the Research Institute) jointly constructed by Huafeng meteorological media group of China Meteorological Administration and meteorological publicity and Science Popularization Center was officially established Based on the interdisciplinary research, multi-cultural integration and wide application of the 24 solar terms, the Research Institute will focus on the scientific exploration of the 24 solar terms, systematically interpret climate change and climate endowments from the perspective of solar terms, produce service products widely demanded by the media and the public, promote the integration of climate change scientific research and the 24 solar terms culture, and promote the integration of natural science and the 24 solar terms culture The inheritance and development of China's excellent traditional culture, customs and wisdom, and the correct guidance of public production and life; at the same time, based on historical meteorological data and climate change characteristics analysis, in-depth research on the connotation of the "24 solar terms" and product creative cooperation Http://news.sciencenet.cn/htmlnews/2019/6/427832.shtm scientists found that the small molecule lung cancer that inhibited lung cancer metastasis is the most malignant tumor in the world and the highest incidence rate and mortality rate in China The main reason for its high mortality rate is metastasis of cancer cells Yang Weiwei, research team of molecular cell science innovation center of Chinese Academy of Sciences and Li Guohui, team of Dalian Institute of Chemical Physics, Chinese Academy of Sciences, have conducted a new study to reveal that uridine diphosphate glucose, a cell metabolite, can effectively inhibit lung cancer metastasis, providing new targets and biomarkers for monitoring and blocking lung cancer metastasis The results were published online recently in the international authoritative academic journal Nature This study reveals for the first time the new function and mechanism of uridine diphosphate glucose inhibiting tumor, which provides the first biochemical marker for the diagnosis of lung cancer metastasis and is helpful for the discovery of early metastasis of tumor Https://www.nature.com/articles/s41586-019-1340-y the successful test run of the next generation of carbon fiber metro train is the first large-scale application of carbon fiber material technology in China's rail trains The car body, bogie frame, cab, equipment cabin and other main load-bearing parts of the train are all made of carbon fiber composite materials, with an overall weight reduction of 13% In addition, the traction system adopts a new and efficient silicon carbide inverter and permanent magnet synchronous traction motor, creating a more energy-saving and environmental friendly "green Metro" Compared with the traditional subway, the comprehensive energy saving of the vehicle is more than 15% Due to the application of new sound insulation and noise reduction materials and equipment, the noise in the passenger compartment has been reduced by more than 5 decibels Compared with the traditional metro, the next generation of metro trains can realize "flexible marshalling", which can match the carriages in the range of 2 to 12 according to the change of passenger flow, so as to reduce the operation cost and improve the operation efficiency Http://www.xinhuanet.com/science/2019-06/28/c_.htm scientists found that the team of Liu Yahong, Professor of Veterinary College of South China Agricultural University, who broke through the "last line of defense", discovered the degradation enzyme tet (x4), which can lead to the deactivation of tegacyclin, from the animal and breeding environment through continuous monitoring It has been found that once bacteria have genes encoding degrading enzymes, they can acquire the ability to degrade all tetracycline antibiotics The results were published online in nature microbiology Tegacyclin is the third generation of tetracycline drugs developed by Pfizer In recent years, tegacyclin has been regarded as the "last line of defense" in the face of the outbreak of carbapenems and myxorubicin resistance The problem of bacterial resistance has become a worldwide problem The discovery of this degrading enzyme may prompt countries around the world to adjust their policies on the use of tetracycline antibiotics, and will also affect the research and development direction and market prospects of tetracycline antibiotics to a certain extent https://www.nature.com/articles/s41564-019-0496-4