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Lung cancer is the leading cause of cancer-related deaths worldwide , accounting for a quarter of all cancer deaths, and the 5-year survival rate for patients with stage I lung cancer is only 57%
Lung cancer is the leading cause of cancer-related deaths worldwide , accounting for a quarter of all cancer deaths, and the 5-year survival rate for patients with stage I lung cancer is only 57%
Recently, a study published in the journal Radiology validated the prognostic value of the two recently proposed CLC definitions by using a method designed to make up for the lack of existing evidence, and studied the effect of quantitative definition of CLC on the prognosis of chest CT .
A total of 436 patients (median age 62 years [interquartile range 55-69 years]; 245 women) were evaluated in this study
In CT, the tumor is located in the hilar 1/3 ( determined by the concentric lines ) and the survival rate was negatively correlated quantitatively determining the position of two-thirds of the lungs is also located an independent prognostic factor higher based on a quantitative definition Time- dependent sensitivity
Figure 1 This figure shows two definitions of central lung cancer: the concentric line from the hilum (yellow line, definition 1) and the concentric line from the midline (solid red line, definition 2) within one-third of the tumor Both are defined as central lung cancer
Figure 1 This figure shows two definitions of central lung cancer: the concentric line from the hilum (yellow line, definition 1) and the concentric line from the midline (solid red line, definition 2) within one-third of the tumor Both are defined as central lung cancer
Figure 2 Axial positioning index of chest CT
Figure 2 Axial positioning index of chest CT
Figure 3 Kaplan-Meier disease-free survival curve stratified according to tumor location
Figure 3 Kaplan-Meier disease-free survival curve stratified according to tumor location
This study shows that , by the concentric lines defined hilar central lung cancer is poor prognosis independent of lymph node status prediction factors
Original source:
Hyewon Choi , Hyungjin Kim , Chang Min Park ,et al.
Hyewon Choi , Hyungjin Kim , Chang Min Park ,et al.
Central Tumor Location at Chest CT Is an Adverse Prognostic Factor for Disease-Free Survival of Node-Negative Early-Stage Lung Adenocarcinomas .
DOI: 10.
1148/radiol.
2021203937 10.
1148/radiol.
2021203937
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