Radiology: Can you identify the components of thrombus and predict the source of stroke without pathology?

Thromboectomy is the best treatment for acute ischemic stroke (AIS) patients with anterior intracranial circulation and great vessel occlusion (LVO) .

Thromboectomy is the best treatment for acute ischemic stroke (AIS) patients with anterior intracranial circulation and great vessel occlusion (LVO) .

CT angiography is the most commonly used imaging method to screen AIS and determine the location of embolization and collateral circulation

Recently, a study published in the Journal of Radiology evaluated whether TE can be reliably displayed on TS-MIP of CT angiography, and explored whether the sign can be used to predict the thrombus composition and the source of stroke in AIS patients caused by LVO in the anterior circulation.

Thrombectomy 

A total of 148 patients were enrolled in this study, with an average age of 71 years and 94 men

TE-positive thrombus contains a higher proportion of fibrin and platelets and fewer red blood cells than TE-negative thrombi.

A, Photomicrographs of thrombus detected from TE positive and TE negative blood vessels

A, Photomicrographs of thrombus detected from TE positive and TE negative blood vessels

In summary, thromboembolic enhancement (TE) is a reliable imaging sign on thin-slice MIP CT angiography in most acute ischemic stroke patients with anterior circulation and great vessel occlusion, providing a preoperative non-invasive evaluation for the clinic Thrombus components and imaging methods to predict the source of stroke

Original source:

Liming Wei , Yueqi Zhu , Jiangshan Deng ,et al.

Liming Wei , Yueqi Zhu , Jiangshan Deng ,et al.
Visualization of Thrombus Enhancement on Thin-Slab Maximum Intensity Projection of CT Angiography: An Imaging Sign for Predicting Stroke Source and Thrombus Compositions .
DOI: 10.
1148/radiol.
2020201548 10.
1148/radiol.
2020201548

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