Radiology: Is the NIHSS score low in patients with acute ischemic stroke suitable for thrombosis therapy?
Last Update: 2020-06-16
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Objective The treatment of stroke patients with mild neurological dysfunction is controversialA recent study of ischemic stroke patients with rtPA treatment showed that patients benefited from rtPA treatment with outnumbered by randomized thrombolytic therapy and aspirin therapyThe purpose of this study was to evaluate the safety and value of thrombotic therapy in acute ischemic stroke patients with a low NIHSS score based on MRI screeningMethods Retrospective analysis of NIHSS database screening patients with NIHSS score of 5 and thrombolytic treatment within 4.5 hours after MRI screening and onsetAN MRI REVIEW WAS PERFORMED 24 HOURS AFTER THROMBOSIS TO ASSESS THE RISK OF CEREBRAL HAEMORRHAGEThe main results were symptomatic intracranial hemorrhage (sICH) and a good 90-day improved RS score (0-1)Subgroup analysis of patients suitable for PRISMS trials included patients withnoneurotic dysfunctionResults Of the 121 patients included, the median age was 65 years, the median NIHSS score was 3, and the female patients were 63%The conversion rate was 13%, of which 11% of patients were speckled bleedingsICH rate of 1%A total of 66 patients had 90 days of prognosis data, of which 74% had good resultsIn the subgroup analysis of 81 patients, no sICH appeared, and a total of 50 patients had 90 days of prognosis, of which 84% had a good prognosisConclusion The thrombolytic therapy in stroke patients with MRI-evaluated and mild neurodysfunction was safeLong-term research in this population will benefit from MRI screening
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