Radiology: MRI myocardial injury patterns in COVID-19 vaccine-associated myocarditis

Myocarditis is a non-ischemic inflammatory disease of the myocardium with diverse etiology, clinical patterns, and prognosis, characterized by inflammation and myocardial cell damage

Myocarditis is a non-ischemic inflammatory disease of the myocardium with diverse etiology, clinical patterns, and prognosis, characterized by inflammation and myocardial cell damage

Post- immunization myocarditis is a rare event that has recently received increasing attention due to reports of myocardial damage in a small number of patients following the administration of messenger RNA (mRNA) -based COVID-19

Cardiac MRI plays an important role in the assessment of acute myocarditis, enabling noninvasive assessment of myocardial tissue

A study published in the journal Radiology examined the pattern and extent of MRI findings of myocarditis associated with COVID-19 vaccination and compared these findings with other causes of myocarditis

This retrospective cohort study included cardiac MRI images of consecutive adult patients with myocarditis with at least one T1-based and at least one T2-based abnormality at a tertiary referral hospital between 2019 and 2021

Of the 92 patients included, 21 (22%) developed myocarditis following COVID-19 vaccination (mean age 31 ± 14 [SD]; 17 were male; 12 [57%] had mRNA-1273, 9 [43%] were BNT162b2)

This study shows that the abnormal pattern of MRI in vaccine-associated myocarditis is similar to that of other etiologies, and the MRI findings tend to be less severe

Original source:

Matteo Fronza, Paaladinesh Thavendiranathan, Victor Chan, et al.

Matteo Fronza, Paaladinesh Thavendiranathan, Victor Chan, et al.
Myocardial Injury Pattern at MRI in COVID-19 Vaccine-associated Myocarditis .
DOI : 10.
1148/radiol.
212559 Myocardial Injury Pattern at MRI in COVID-19 Vaccine-associated Myocarditis 10.
1148/radiol.
212559

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