echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Antitumor Therapy > Radiology: What effect will the use of gadolinium contrast agent have on brain tissue?

    Radiology: What effect will the use of gadolinium contrast agent have on brain tissue?

    • Last Update: 2021-08-03
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

     About the gadolinium contrast link between agents (GBCAs) and nephrogenic systemic fibrosis and GBCA in brain tissue accumulation was found , it caused the people to this type of contrast agent generated considerable research interest in the biological role


     About the gadolinium contrast link between agents (GBCAs) and nephrogenic systemic fibrosis and GBCA in brain tissue accumulation was found , it caused the people to this type of contrast agent generated considerable research interest in the biological role


    Most previous studies have used T1 signal enhancement as a measure of potential gadolinium accumulation in brain tissue .


    Recently, a study published in the journal Radiology explore the QSM in the detection of primary brain tumors in patients with continuous use of macrocyclic type GP DN and the magnetic susceptibility changes after GBCA ability for people to further clarify the GBCA provides theoretical support mechanism of action , Which paved the way for the wide application of QSM in clinical practice


    Diagnosis of gadobutrol GBCA gadobutrol

    This study analyzed a total of 199 MRI scans of 90 patients (mean age 51 years ± 17 years [standard deviation]; 51 men)


    Gadobutrol injection frequency and GP --3 gadobutrol and DN --3 gadobutrol susceptibility related to gadobutrol injection frequency is still an independent predictor of increased susceptibility GP --3 gadobutrol -3 -3 gadobutrol There is no correlation between the number of injections and SI or susceptibility in DN

    Fig.


    Fig.


    The table shows the relationship between the MRI signal ratio of globus pallidus and dentate nucleus and the magnetic sensitivity value in the multivariate calibration model


    The table shows the relationship between the MRI signal ratio of globus pallidus and dentate nucleus and the magnetic sensitivity value in the multivariate calibration model


    This study proves that the magnetic susceptibility of gadobutrol in patients with repeated injections of gadobutrol is positively correlated with the number of injections of gadobutrol .


    Original source:

    Yangsean Choi , Jinhee Jang , Jiwoong Kim , et al.


    Choi Yangsean , Jinhee Jang , Jiwoong Kim , et Al.
    The MRI and Quantitative Magnetic Susceptibility Maps of The Serial After the Administration of Gadobutrol Brain: A Longitudinal the Follow-up Study .
    The DOI: 10.
    1148 / radiol.
    2020192579 10.
    1148 / radiol.
    2020192579

    in this message
    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.