Reactions that may produce dangerous products (by-products) (3)

2.

example 1

Application process: omitted

Remarks: HCN is produced during the reaction, exhaust gas absorption is required, and online HCN detection is required.

Example 2

Application process: Add sodium methoxide (1mol/L, 5mmol) to the methanol (100mL) solution of compound A (5.

Remarks: HCN and NaCN are generated during the reaction.

Example 3

Application process: Dissolve compound A (28g, 0.

Remarks: Phosphorus pentasulfide (P2S5 or P4S10) is used as a vulcanizing reagent to convert the oxygen in alcohol and carbonyl into corresponding thio compounds

Example 4

Declared process: the above compound is heated and refluxed in toluene to detect the end point, quenched with 4L saturated NaHCO ₃ aqueous solution containing 400 mL of methanol , and extracted with DCM (2L×3) .

Remarks: The product belongs to isonitrile, has a strong stench, and is disgusting.

Example 5

Application process; under the protection of nitrogen at -40°C, add compound A (2.

Remarks: The product isocyanate has a special pungent odor, and has a small molecular weight and is volatile, which aggravates the degree of damage

Related links: Reactions that may produce dangerous products (by-products) (2)