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    Home > Active Ingredient News > Immunology News > Repeated oral ulcers are "white plug disease"? Pay attention to this kind of identification!

    Repeated oral ulcers are "white plug disease"? Pay attention to this kind of identification!

    • Last Update: 2020-07-21
    • Source: Internet
    • Author: User
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    May 20 is the international day of care for Behcet's disease.Behcet's disease is a systemic autoimmune disease with unknown etiology. Its pathological manifestations are systemic vasculitis. The main symptoms are recurrent oral ulcer, genital ulcer, ophthalmia and skin damage. It can also involve blood vessels, nervous system, digestive tract, joint, lung, kidney, epididymis and other organs. Most patients have a good prognosis The prognosis was poor.Behcet's disease can be found in all kinds of people in China, from teenagers to the elderly, but it is more common in young people aged 16-40 years, both men and women.May 20 is the "international day of care for Behcet's disease". In order to improve the public's attention and correct cognition of Behcet's disease, early diagnosis and treatment, and improvement of the quality of life of patients with Behcet's disease, let's understand the knowledge of Behcet's disease.01 the typical symptom of Behcet's disease is recurrent oral ulcer. The "report on the survival status of Chinese Behcet patients in 2019" lasted for nearly five years. Based on 2200 one-on-one questionnaire survey, it was found that more patients with Behcet's disease had oral / genital ulcer and skin damage as the first symptoms.according to the survey, oral ulcer was the first symptom of Behcet's disease, and it also had the highest proportion, up to 99.5% (98.3% in 2017); genital ulcer and skin damage accounted for 70.9% (70.8% in 2017) and 67.1% (62.8% in 2017), followed by joint pain, eye inflammation and other organs The official was damaged.in terms of organ involvement, Behcet's disease patients with eye damage accounted for 31.4%.the cause of Behcet's disease has not been fully identified, which may be related to heredity, infection and living environment.a patient with Behcet's disease may have multiple symptoms, but each symptom appears at different times.the most terrible thing is that the initial symptoms of Behcet's disease are not obvious. Symptoms like oral ulcer are easy to be ignored. When the eyes and joints are involved, they think it is simple eye inflammation and joint pain, which is easy to cause delayed diagnosis and misdiagnosis.in fact, half of patients with Behcet's disease need more than five years to be diagnosed.the survey shows that the earliest age of Behcet's symptoms is between 19 and 50 years old, accounting for about 60%, and the majority of patients are 19-30 years old.from the onset of symptoms to the final diagnosis, most patients experienced a long time, and the number of patients who could not be diagnosed for more than five years has exceeded half of the total number, reaching 53.86% (48.84% in 2017).02 oral ulcer and buccal plug, how to distinguish? Oral ulcer is one of the main symptoms of Behcet's disease, which is often mistaken by patients as ordinary oral ulcer and delayed diagnosis and treatment. The differences between the two are as follows: 1. Oral ulcer of Behcet's disease occurs repeatedly, and the symptoms are generally more serious than that of ordinary oral ulcer, and can not be completely relieved by taking vitamin and trace elements or paying attention to oral hygiene; 2 In addition to recurrent oral ulcer, the disease can also be accompanied by a variety of symptoms, such as recurrent genital ulcer; eye damage, such as recurrent uveitis, retinal vasculitis; skin damage, such as pseudofolliculitis, pleomorphic erythema; disease involving other systems can also produce corresponding symptoms, while ordinary oral ulcer does not produce damage to other systems; 3 Behcet's disease examination can be found in patients with a variety of antibodies positive, suggesting that the disease is related to the autoimmune system, and the ordinary oral ulcer related antibody detection is mostly negative; 4, simple oral ulcer, the shape will be smaller, and the diameter is generally not more than 1 cm.but the ulcer area of Behcet's disease is larger and its shape is more irregular.therefore, if we judge the two from the shape, we can also distinguish them well.when common oral ulcer occurs repeatedly, it is difficult to distinguish the patients with Behcet's disease who only showed oral ulcer at the initial stage. Therefore, the vigilance of patients and doctors should be improved. For patients with recurrent oral ulcer, relevant examinations should be improved to make a clear diagnosis, and timely detection and intervention of Behcet's disease can relieve the patient's pain and delay the progress of the disease. 03 to treat Behcet's disease, do these four points well! In fact, nearly 70% of patients with Behcet's disease insist on treatment and their condition is stable. the statistical results show that 69.2% of patients are in stable condition while taking medicine, 13% have stopped taking medicine (lower than the data in 2017). However, 15.3% of patients with Behcet's disease are still under treatment but their condition is not effectively controlled, and 2% of patients are not treated for various reasons, and their condition is not controlled (lower than the proportion in 2017). it can be seen that patients with Behcet's disease have a more and more positive attitude towards treatment; although they can not get rid of the disease completely, they still have the possibility to stop taking drugs. the key to the treatment of Behcet's disease is early diagnosis and early treatment. The main points of treatment are as follows: 01. We should pay attention to the rescue signals sent by the body to us at ordinary times, so as to achieve early detection, early diagnosis and early treatment. 02. If vasculitis and vascular embolism occur repeatedly at the same time of oral ulcer, in addition to symptomatic treatment, rheumatologists should be consulted to give immunosuppressive treatment, which is very important to reduce mortality and improve the cure rate. 03. Behcet's disease is mainly controlled by immunosuppressive agents, including low-dose hormone, thalidomide, cyclophosphamide, etc. 04. We should adhere to regular follow-up in rheumatology clinic, regularly evaluate the curative effect and systemic system, and avoid believing in folk prescriptions and visiting doctors, which will delay the disease. reference sources: 1. Survival status report of Chinese patients with Behcet's disease in China [J]. Chinese Journal of general practitioners, 2005, 004 (011): 666-667.3, Zheng Wenjie, Li Lu. Interpretation of the latest EULAR guidelines for clinical management of Behcet's syndrome in 2018 [J]. Chinese Journal of clinical immunology and allergy, 2018, 012 (003): 259-262
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