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Human induced pluripotent stem cells (hiPSCs) allow in vitro research on genetic diseases and have the potential for individualized stem cell therapy.
This new method can generate genetically corrected autologous pluripotent stem cells from 2-3 mm skin biopsies of patients with different genetic diseases.
The long-term goal of researchers is to produce autologous cells with therapeutic properties.
In summary, the results of this article show that the new method developed by the researchers can generate dozens of gene-edited hipsC monoclonal cell lines, which has the efficiency and stability of the previous actions, and can greatly reduce the cost of cell culture.
Note: The original text has been deleted
Original source:
Sami Jalil, Timo Keskinen, Rocío Maldonado, et al.