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Drugs used to treat AIDS and HIV may give hope to patients diagnosed with the most common primary brain tumors
This breakthrough, co-funded by the charity brain tumor research, is of great significance, because if further research concludes, antiretroviral drugs can be used to diagnose brain tumors of meningioma and acoustic neuroma (also called schwannoma) Patient
Because these tumor types often recur after surgery and radiotherapy, there are very few treatment options, so there is an urgent need for more effective methods
Meningioma is the most common primary brain tumor
Researchers at the Brain Tumor Research Center of the University of Plymouth have previously demonstrated that a tumor suppressor called Merlin contributes to the formation of meningioma, acoustic neuroma and ependymoma tumors
In this latest study, senior researcher Dr.
Dr.
Professor Oliver Hahnemann, Director of the Center for Excellence in Brain Tumor Research, said: "It is important that these drugs - retroviral protease inhibitors such as atazanavir, and lopinavir - have been approved for the treatment of HIV/AIDS in the United States and the United Kingdom.
Hugh Adams, a spokesperson for Brain Tumor Research, said: "These findings are significant because drug reuse is a valuable way to accelerate the testing of new methods in clinical trials.
"This is especially important for brain tumor patients, because many of them don't have that much time
Article title
Human endogenous retrovirus type K promotes proliferation and confers sensitivity to anti-retroviral drugs in Merlin-negative schwannoma and meningioma