Research group of Professor Yang Yingwei of Jilin University: in situ preparation of gold nanoparticles by water soluble inclined column [6] aromatics and its application

Introduction the design, synthesis and functionalization of new supramolecular macrocyclic molecules not only inject fresh energy into molecular recognition, self-assembly and the extension and expansion of assembly functions, but also provide inexhaustible power for the construction and application of functional organic-inorganic hybrid materials In recent years, Professor Yang Yingwei's research group of Jilin University has carried out a series of innovative work in the design, synthesis and application development of new supramolecular macrocyclic receptors Recently, they prepared gold nanoparticles in situ by water-soluble inclined column [6] arene and studied their application Relevant research results were published in organic letters (org Lett 2019, 21, 5215-5218) Professor Yang Yingwei's research group was founded in March 2011 The research project aims to design and synthesize new organic supramolecular macrocyclic compounds and construct self-assembled functional system and intelligent organic-inorganic system under the guidance of biomedicine, environmental sustainable development and energy storage- Polymer hybrid composite materials, porous or non porous organic crystal functional materials are used in drug targeted delivery and controlled release, gas / hazardous selective adsorption separation, pesticide sensing and detection, photoelectric functional materials and other specific applications A / B / C, 130 papers have been published in international important professional journals such as chem EUR J., polymer Chem., SCI China chem., chin Chem Lett Professor Ying Wei Yang, Professor Ying Wei Yang, Professor of School of chemistry, Jilin University, nanoarchitecture international cooperation laboratory, doctoral supervisor In 2000, he graduated from the Department of chemistry of Nankai University and obtained his bachelor's degree In the same year, he was sent to Nankai University for direct research, studied under Professor Liu Yu, and obtained his doctor of Science degree from Nankai University in 2005 From 2005 to 2010, he successively worked in Arizona State University, University of California, Los Angeles and University of California, Irvine is engaged in postdoctoral research, and his co mentors are Professor John C Chaput (currently working at the University of California, Irvine), Professor Sir Fraser Stoddart (Nobel Prize winner in chemistry in 2016, foreign academician of the Chinese Academy of Sciences, now working at Northwestern University in the United States) and Professor Zhibin Guan Since 2011, he has worked in the school of chemistry, Jilin University, mainly engaged in the research of organic supramolecular chemistry and materials Up to now, he has published more than 160 SCI papers and has been invited to write five chapters of his monograph The research work was specially reported or commented by nature, nature chemistry, nature materials, Science Daily, ACS newsworthy chemistry, chemistry world, chemistry views, Elsevier, materials views China and other magazine media As the evaluation expert or invited reviewer of foundations at home and abroad, such as European Commission, Israel science foundation, Belgium Flanders research foundation, Chile National Science and Technology Commission, British Lung Foundation, Poland National Science Center, National Natural Science Foundation, Postdoctoral Science Foundation, etc.; matter (Cell Press), Chinese Chemical Letters, More than 100 important SCI magazines, such as scientific reports, nature communications, acc chem Res., chem SOC Rev., adv mater., J am Chem SOC., angel Chem Int ed., ACS Nano, adv.funct Mater., etc., have invited reviewers He presided over four general programs of the National Natural Science Foundation, more than ten doctoral programs of the Ministry of education and other funds of various types of provincial and university Selected as "global highly cited scientist" (Chemistry), Elsevier "China highly cited scholar" (Chemical Engineering), Royal Chemical Society "top 1% highly cited Chinese author", Royal Chemical Society 2015 chemcomm emerging investigator, Royal Chemical Society 2019 polymer chemistry pioneer Investigator , the Sixth Batch of top innovative talents in Jilin Province, and Jilin University's training project Leading scientific research achievements: in situ preparation of gold nanoparticles by water-soluble inclined column [6] aromatics and its application; Yang Yingwei research group of Jilin University has carried out a series of innovative research work in the field of traditional column / calixarene supramolecular chemistry and materials since its establishment in 2011, and accumulated rich research experience in macrocyclic chemistry and organic supramolecular materials (org BIOMOL Chem 2012 , 10 , 9405; J Am Chem Soc 2013 , 135 , 1570; Small
2013 , 9 , 3224; Acc Chem Res 2014 , 47 , 1950; Chem Sci 2014 , 5 , 2804; Adv Mater 2014 , 26 , 7027; Chem Sci 2015 , 6 , 1640; Small
2015 , 11 , 3807; Adv Mater 2017 , 29 , 1606134; Adv Mater 2018 , 30 , 1800177;
ACS Appl Mater Interfaces
2018 , 10 , 34655; Chem
2018 , 4 ,2029; Small
2019 , 15 , 1805509; Research
2019 , https://spj.sciencemag.org/research/aip/1454562/ ; Matter
2019 , DOI: 10.1016/j.matt.2019.03.005 ）。 In recent years, the research group has gradually shifted its focus to the design, synthesis and functional supramolecular assembly of new supramolecular macrocyclic aromatics, carried out some research work, and had an important impact in the field In 2016, the research team designed and synthesized biphenyl extended column [6] arene with larger cavity and smaller steric hindrance for the first time Its molecular crystals have potential applications in purification and separation of petrochemical products such as xylene and benzene (chem Commun., 2016, 52, 5804) In 2018, the research group designed and synthesized inclined column [6] aromatics (i.e inclined tower aromatics) for the first time, which has important potential application value in the fields of supramolecular energy materials, molecular machines, crystal engineering, etc (angel Chem Int ed., 2018, 57, 9853) In 2019, the research group further prepared a series of biphenyl extended type aromatics functional derivatives, and constructed a new supramolecular polymer system, and then realized the detection and separation of mercury ions in water by using the supramolecular assembly induced luminescence mechanism (j.am Chem SOC., 2019, 141, 4756) At the same time, it is worth mentioning that the members of the research team also made full use of the key intermediate in the design and synthesis of new macrocyclic aromatics, and successfully obtained a new type of open-ended supramolecular receptor called "molecular clamp", which is used as a non porous molecular crystal material for high efficiency iodine solution and iodine vapor adsorption, and realized the new function of "molecular crystal transmission" (ACS appl Mater Interfaces 2019 , 11 , 998 ）。 In addition, Professor Yang Yingwei was invited to review the opportunities and challenges in the field of design and synthesis of new macrocyclic aromatics in recent years in the Journal of chemical communications (chem Commun., 2019, 55, 1533) Recently, on the basis of the previous work, awlp6 was designed and synthesized for the first time, and used as stabilizer and reductant to control the growth of gold nanoparticles in situ In addition, they further studied the application of awlp6 AuNPs in self-assembly, sensor detection and green catalysis (Figure 1) Figure 1 Awlp6 AuNPs and its application in self-assembly, sensor detection and green catalysis (source: org Lett.) first, the author designed and synthesized the first water-soluble anion functionalized inclined column [6] aromatics (awlp6) (Figure 2) Awlp6 contains eight carboxylates, which can not only reduce Au (III) to prepare spherical gold nanoparticles, but also regulate and stabilize gold nanoparticles by the support of cavity skeleton structure and electrostatic repulsion between carboxylates Fig 2 The synthesis route of water-soluble inclined column [6] arene (source: org Lett.) later, the author selected four guest molecules (quaternary ammonium modified tetraphenylethylene derivative, 4q-tpe) with awlp6 recognition sites to study the self-assembly behavior of awlp6-aunps It was found that awlp6 AuNPs self-assembled from one dimension to three dimensions with the increase of 4q-tpe content, accompanied by significant changes in UV Vis and solution color (Fig 3) This not only fully proves that awlp6 endows AuNPs with unique host guest recognition performance, but also can be used for super sensitive detection of guest molecules Fig 3 4q-tpe regulates awlp6-aunps self-assembly (source: org Lett.) because the molecular size of paraquat (methyl viologen, MV) is matched with the cavity size of awlp6, there is significant host guest bond cooperation between them Therefore, the author uses the area integral ratio method of aggregation state and monodisperse state awlp6-aunps in UV-Vis The detection limit (0.02 ppm) of trace MV and its derivatives (bisviologen, BIS MV) in aqueous solution is lower than the national standard (0.03 ppm for grains, 0.05 ppm for fruits and vegetables) of pesticide residues in grains and fruits and vegetables (Figure 4) Fig 4 trace detection of MV and its derivative Bis-MV by AWLP6-AuNPs (source: Org Lett.) finally, due to the regulation and stability of AWLP6 giving gold nanoparticles moderate particle size and good stability, the author studied the high catalytic activity of AWLP6-AuNPs for the reduction of p-nitrophenol (Fig 5) Figure 5 Awlp6-aunps' green catalysis for the reduction of p-nitrophenol (source: org Lett.) to sum up, the author designed and synthesized water-soluble slant column [6] arene (awlp6) for the first time, which can not only be used as reductant and stabilizer for in-situ regulation and stabilization of gold nanoparticles, but also give unique host guest recognition characteristics to AuNPs In addition, the application of awlp6 AuNPs in self-assembly, sensor detection and green catalysis was studied This work not only has important guiding significance for the design and synthesis of new macrocyclic aromatic derivatives, but also provides a new perspective and effective strategy for the precise regulation and multiple applications of organic-inorganic hybrid nanomaterials based on supramolecular macrocycles and inorganic nanoparticles The research results were recently published in the journal organic letters s of the American Chemical Society (org Lett 2019, 21, 5215-5218) The first author of this paper is Wang Xin, a 2015 master of Chemistry College of Jilin University, and the corresponding author is Professor Yang Yingwei The cooperative postgraduates include Wu Jiarui, doctoral student of the research group, and Liang Feng, teacher of Wuhan University of science and technology The research was supported by the general program of National Natural Science Foundation of China (2187110851673084) and the special fund for new materials of Jilin Province university joint construction plan (sxgjsf2017-3) Review of previous reports: new achievements of Professor Yang Yingwei's research group of Jilin University: supramolecular assembly induced fluorescence enhancement for mercury detection and removal Research group of Professor Yang Yingwei of Jilin University: water soluble biphenyl extended column