Researcher Li Dajing, Research Institute of Agricultural Products Processing, Jiangsu Academy of Agricultural Sciences: Stevioside encapsulation promotes lutein bioavailability and its mechanism of action

Original title: Researcher Li Dajing, Research Institute of Agricultural Products Processing, Jiangsu Academy of Agricultural Sciences: Stevioside encapsulation promotes lutein bioavailability and its mechanism of action

Li Dajing, Dai Zhuqing, Song Jiangfeng and others from the Research Institute of Agricultural Products Processing, Jiangsu Academy of Agricultural Sciences published an online research article titled "Study on the bioavailability of stevioside-encapsulated lutein and its mechanism" on Food Chemistry (IF=6.

Highlights

• Lutein:OH- Stevioside:O hydrogen bond, CH-π interaction and van der Waals force work together to make lutein well in the hydrophobic cavity of stevioside to form LUT-STE nanoparticles;
• In vitro Caco-2 cell model and in vivo mouse metabolic kinetics model showed that stevioside nano-encapsulation significantly promoted the bioavailability of lutein;
• LUT-STE is mainly transported across the membrane through passive diffusion and endocytosis mediated by clathrin and pit/lipid;
• CD36, NPC1L1 and PPARγ proteins assisted the transmembrane transport of LUT-STE.
  
  

  Introduction

  Lutein is a natural carotenoid containing two different ionone rings.

  
  

  Nano-encapsulation is one of the effective methods to improve the bioavailability of hydrophobic nutrients.

  
  

  Results and Discussion

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  About the Author

  Li Dajing

  Li Dajing, PhD, master supervisor, researcher.

  
  

  Song Jiangfeng

  Song Jiangfeng, PhD, Master Supervisor, Associate Researcher.

  
  

  Liu Jun

  Liu Jun, professor and doctoral supervisor of the School of Food Science and Engineering, Yangzhou University, has long been engaged in food carbohydrate related research work, including functional active polysaccharides, polysaccharide-polyphenol graft copolymers and polysaccharide-based food active smart packaging films; Has presided over 2 National Natural Science Foundation projects; as the first author and corresponding author, published 76 SCI papers in Comprehensive Reviews in Food Science and Food Safety, Chemical Engineering Journal, Food Hydrocolloids and other journals, H-index = 28, of which 8 These papers were selected as ESI Highly Cited Papers, as top talents of Yangzhou University and outstanding young backbone teachers of the Qinglan Project of Jiangsu Province.

  
  

  Dai Zhuqing

  Dai Zhuqing, PhD, master supervisor, assistant researcher.