Researchers at Columbia University have discovered that the key gene that causes obesity ——— 14-3-3 proteins.

In a recent study published in the international journal Nature Communications, researchers from the University of British Columbia have found key genes that can trigger obesity.
the gene is present in all cells of the body and can encode a protein called 14-3-3.
researchers said that when the expression of the gene was silenced in the mouse body, it led to a 50 percent drop in the specific type of unhealthy white fat in mice, which is directly related to obesity, heart disease and diabetes;
Earlier this year, researchers found that more than 100 regions of the human genome are directly related to obesity, which appears to trigger obesity by regulating the brain's feelings of hunger and the distribution of fat in the body, but in the original study researchers did not identify genes that encode 14-3-3 proteins, which control the production and growth of fat cells.
the study, researchers linked special proteins to fat production and provided some ideas for the development of new obesity drug therapies, which scientists believe can inhibit fat build-up in overweight individuals by inhibiting the gene or blocking the expression of the gene-coded protein;
researchers looked at the 14-3-3 protein family four years ago and found that the protein is present in unhealthy adipose tissue in obese individuals, and this study not only identifies the true behind-the-scenes drivers of the protein, but also sheds light on the causal relationship between 14-3-3 protein and fat accumulation.
Researchers have so far failed to know how genes encoded 14-3-3 proteins affect obesity in the body, and this study provides some help in explaining this.
obesity is often directly related to an increased risk of diabetes, heart disease and certain cancers, where obesity consumes $2 trillion a year, more than a quarter of Canadians are obese individuals, and obesity is soaring, and we don't know how fat cells are produced, but we know how current research is used to help develop new strategies to curb obesity.
Source: Decoding Medicine.