Researchers have developed nanoparticles that can target white blood cells that cause acute lung inflammation

Researchers investigated how neutrophils distinguish between destroyed bacteria and other compounds in the blood, such as cholesterol particles

"We hope to use the existing functions of neutrophils to identify and eliminate invaders to inform how to design a'Trojan horse' nanoparticles.

Acute respiratory failure and acute respiratory distress syndrome are life-threatening forms of respiratory failure with high morbidity and mortality

To solve acute respiratory distress syndrome and other medical problems, researchers at the University of Pennsylvania and elsewhere have been using nanoparticles to concentrate drugs in injured or diseased organs

This group of scientists pointed out that although there is still a long way to go in the development of a feasible treatment for ALI/ARDS that uses nanoparticles to provide treatment through neutrophils, this research represents a step forward in understanding the status and function of the immune system.

"Now that we have determined that neutrophils will patrol nanoparticles with agglutinin, our next step is to understand how and why other microorganisms, such as viruses, these rigid and symmetrical microorganisms have evolved to avoid neutrophils.

This research was funded by the National Institutes of Health (R01 HL125462)

Journal Reference :

1. Jacob W.