Response risk assessment: the "safety belt" of fine chemicals

"Global Coatings Network News"

"Global Coatings Network News"

The theme of this year's Work Safety Month is "Life First, Safe Development", emphasizing that safety is an important prerequisite for development.

The theme of this year's Work Safety Month is "Life First, Safe Development", emphasizing that safety is an important prerequisite for development.

"Reaction risk research, as an important technical guarantee for engineering scale-up, process design, and safe production, is an indispensable key technical content in the technology development chain.

We often use the refinement rate to measure the development level of a country's chemical industry.

"Fine chemical production accidents are often caused by out-of-control reaction heat, especially chemical processes such as nitrification, sulfonation, oxidation, etc.

He particularly emphasized that for fine chemical companies, 2020 is a key node.

“People who don’t understand the response security risk assessment will think that this is a very imaginary job.

Since the out-of-control of the reaction heat is the original culprit of the fine chemical industry, the reaction safety risk assessment focuses on the control of the reaction heat.

The first is to conduct thermal stability tests on the raw materials, intermediate materials, products and other chemicals involved in the reaction, to obtain the decomposition heat of the substances, and to carry out the evaluation of the thermal stability of the substances; the second is to evaluate the release rate by testing the reaction temperature rise.

The fine chemical reactions involved in the pharmaceutical process are very typical, and pharmaceutical companies have become the focus of safety risk assessment.
The reporter learned in an interview with Zhejiang Huaqi Safety Technology Co.
, Ltd.
, which specializes in the safety risk assessment of fine chemical reactions, that they chose a pharmaceutical factory as the evaluation object.
The purpose of the evaluation is very clear.
Measures are taken to reduce the risk level and achieve intrinsic safety for the 4th and 5th levels of the reaction; the second is to analyze the reaction process through the measurement of the reaction heat, and make process improvements accordingly to achieve "cost reduction, quality improvement, and reduction The purpose of "pollution" is to realize green pharmaceuticals.

The fine chemical reactions involved in the pharmaceutical process are very typical, and pharmaceutical companies have become the focus of safety risk assessment.
The reporter learned in an interview with Zhejiang Huaqi Safety Technology Co.
, Ltd.
, which specializes in the safety risk assessment of fine chemical reactions, that they chose a pharmaceutical factory as the evaluation object.
The purpose of the evaluation is very clear.
Measures are taken to reduce the risk level and achieve intrinsic safety for the 4th and 5th levels of the reaction; the second is to analyze the reaction process through the measurement of the reaction heat, and make process improvements accordingly to achieve "cost reduction, quality improvement, and reduction The purpose of "pollution" is to realize green pharmaceuticals.

"We first carried out tracking tests on the process, and proposed a laboratory process optimization plan based on the data obtained, and then researched and completed process amplification with the cooperation of the technical department.
The optimized process equipment has achieved significant improvements in safety and at the same time.
Very good cost reduction and emission reduction effect: the amount of raw materials is reduced by 80%, the cost is reduced by 50.
3%, the exhaust gas emissions are reduced by 80%, and the waste liquid generation is reduced by 50%.
" The technical director of Huaqi Company introduced to reporters.

"We first carried out tracking tests on the process, and proposed a laboratory process optimization plan based on the data obtained, and then researched and completed process amplification with the cooperation of the technical department.
The optimized process equipment has achieved significant improvements in safety and at the same time.
Very good cost reduction and emission reduction effect: the amount of raw materials is reduced by 80%, the cost is reduced by 50.
3%, the exhaust gas emissions are reduced by 80%, and the waste liquid generation is reduced by 50%.
" The technical director of Huaqi Company introduced to reporters.

Risk assessment becomes industry consensus

Carrying out response safety risk assessment is not only the need of the enterprise's own development, but also the need of government supervision, and it is also the need of industrial upgrading.
This understanding has become the consensus of the fine chemical industry.

Carrying out response safety risk assessment is not only the need of the enterprise's own development, but also the need of government supervision, and it is also the need of industrial upgrading.
This understanding has become the consensus of the fine chemical industry.

For enterprises, carrying out reaction safety risk assessment can provide a basis for enterprises to develop products, and eliminate products with high process risk in advance in the research and development stage.
The reaction risk safety assessment of existing products can promptly discover potential safety hazards in existing processes and prevent them before they happen.
This is a bit like putting an extra "safety belt" on production.

For enterprises, carrying out reaction safety risk assessment can provide a basis for enterprises to develop products, and eliminate products with high process risk in advance in the research and development stage.
The reaction risk safety assessment of existing products can promptly discover potential safety hazards in existing processes and prevent them before they happen.
This is a bit like putting an extra "safety belt" on production.

For the government, responding to the safety risk assessment conclusions can also provide a basis for government decision-making.
For example, the hazardous chemical safety standards compliance acceptance assessment clearly requires enterprises to carry out risk management, and the "Guiding Opinions" also clarifies the scope and time of response risk research.
Claim.

For the government, responding to the safety risk assessment conclusions can also provide a basis for government decision-making.
For example, the hazardous chemical safety standards compliance acceptance assessment clearly requires enterprises to carry out risk management, and the "Guiding Opinions" also clarifies the scope and time of response risk research.
Claim.

For the industry, reducing reaction safety risks through process optimization will reduce the overall safety risks of the fine chemical industry in the long run, which will promote the reshaping and upgrading of the entire industry's image.

For the industry, reducing reaction safety risks through process optimization will reduce the overall safety risks of the fine chemical industry in the long run, which will promote the reshaping and upgrading of the entire industry's image.

The reaction types that require risk assessment include phosgene and phosgenation, electrolysis, chlorination, nitrification, fluorination, hydrogenation, diazotization, oxidation, peroxide and more than 20 reaction types, involving pesticides, dyes, coatings, More than 10 types of industries including chemical reagents and electronic chemicals.
"The market for responding to safety risk assessment will be very large.
In addition, the later process optimization and the development of safety processes will activate new market demands.
" Researcher Zhang Fuli is very optimistic about the market prospects of this technology.