Resveratrol glycoside can lower blood sugar after meals, study finds

Original title: Study found that: resveratrol glycoside can reduce after-dinner blood sugar
Reporter 17 from
China
Academy of Sciences Northwest Plateau
biology
research institute was informed that the plant restoration and medicinal plant resources research group found that resveratrol glycoside can reduce post-meal blood sugar, the study for the development of treatment of diabetes after-dinner hyperglycemia provides an alternative compound.
resveratrol glycoside is widely distributed in plants, high content, at least 70 species of plants have been found resveratrol glycoside, the Chinese Academy of Sciences Northwest Plateau Biological Research Institute vegetation restoration and medicinal plant resources team in Tanggute huang found the phyto effect.
Tanggut Yellow is located in Gansu, Qinghai and Qinghai, China, along the border with Tibet. It grows in alpine valleys between 1600 and 3000 meters above sea level.
Zhao Xiaohui, an associate researcher at the Northwest Plateau Biological Research Institute of the Chinese Academy of Sciences, said that resveratrol glycosides have significant alpha-glucosidease inhibition activity through systematic separation and screening of chemical components in Tanggut huang, which can inhibit the increase of blood sugar after meals in diabetic model mice.
It is understood that diabetes is a chronic metabolic disease, mainly manifested in high blood sugar, as well as serious diabetes complications, including coronary artery disease, stroke, perennial artery disease, retinal lesions, kidney disease and neuropathy.
blood sugar levels after meals is an effective treatment for diabetes and the prevention of diabetes-related complications. Zhou Guoying, a researcher in biology at the Northwest Plateau of the Chinese Academy of Sciences, said a-glucosidease inhibitors have been recommended as a first-line drug for diabetes, but the side effects of such drugs on the gastrointestinal tract are greater, making clinical restrictions. Therefore, screening high-efficiency and low-toxic alpha-glucosidease inhibitors from natural products is a hot topic in this field.
in vivo, oral resveratrol glycoside significantly inhibited increased blood sugar after meals in normal mice and diabetic mice, and showed dose dependence. Zhao Xiaohui introduced, "In addition, through enzyme dynamics analysis and molecular docking experiments, the competitive inhibition mechanism of resveratrol glycoside to alpha-glucosidease was determined." "
, according to the International Diabetes Federation, the prevalence of diabetes in urban areas is much higher than in rural areas, with three-quarters of people living with diabetes living in cities by 2045." The global goal of Urban Change Diabetes is to reduce the incidence of obesity by 25 per cent, thereby reducing the prevalence of diabetes to less than 10 per cent by 2045.
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