Revealing the experience and attitude of clinical research of Chinese doctors

Source: in order to understand the practice and true attitude of different types of doctors to clinical research, and provide reference for relevant policy makers and enterprise managers, pharmaceutical economic news 2015-06-12, sponsored by pharmaceutical management major of Tianjin University and cooperated with Guangzhou Yushi Pharmaceutical Technology Co., Ltd., carried out“ A survey of the practice and attitude of Chinese doctors in clinical research The survey was conducted anonymously on the Internet for one month 258 questionnaires were collected and 217 valid ones were confirmed This survey is the first academic research on the practice and attitude of Chinese doctors' clinical research in China The results show that the main factors that affect doctors' interest in clinical research are: first, providing patients with new treatment methods; second, learning opportunities of clinical research methods; third, systematic support from hospitals Who is the lead singer? 72.4% of them have participated in domestic multicenter clinical research, only 30.5% of them have participated in international multicenter clinical research; beishangguang district and Affiliated Hospital of university are the main subjects of current Chinese clinical research, and the subjects of this survey are doctors who have participated in or are participating in clinical research, and their hospitals are located in 21 provinces and cities, of which 48.8% are located in Beijing, Shanghai and Guangzhou Among the first tier cities, 95.9% are grade three hospitals, 64.5% are affiliated hospitals of universities, and 84.8% are clinical drug testing institutions Among the respondents, 42.9% were male, 77.5% were under 40 years old, 61.7% were attending doctors and residents, and 51.2% were physicians 68.2% of the doctors surveyed had the national GCP training certificate 72.4% of the investigated doctors participated in the domestic multi center clinical research, while only 30.5% participated in the international multi center clinical research Further analysis shows that in addition to domestic multi center clinical research, the proportion of researchers in beishangguang area participating in other kinds of clinical research is significantly higher than that in other regions, and the proportion of university affiliated hospitals is also significantly higher than that of non affiliated hospitals, which reflects that beishangguang area and university affiliated hospitals are the main body of clinical research in China at present Only 42.4% of the surveyed doctors participated in more than three clinical studies, and there was no significant difference between doctors from different regions and hospitals 73.7% of the surveyed doctors play the role of secondary investigator, 8.3% of them play the role of primary investigator and others play the role of clinical coordinator How specialized is it? Only 50.2% had the experience of centralized random system, 28.1% had the relevant international conference or training experience; the affiliated hospitals of beishangguang region and universities were obviously superior in clinical research related experience, international conference or training experience; whether they understood the declaration of Helsinki of the World Medical Association 67.8% Of the doctors surveyed said they fully or mostly understood the declaration Among the doctors in university affiliated hospitals, the proportion reached 75%, and among the doctors with national GCP training certificate, the proportion reached 80.6% This shows that the national GCP training system for doctors is still effective 56.2% of the surveyed doctors need 15-30 minutes to talk with the patients about their knowledge, and 83.8% of the surveyed doctors need less than 30 minutes to talk about their knowledge Compared with similar surveys in Japan and the west, Chinese researchers spend significantly less time talking about knowledge 74.2% of the surveyed doctors have cooperated with the clinical research coordinator in the research, while only 50.2% of the respondents have the experience of centralized random system Further analysis shows that the proportion of researchers with the above four related experiences in beishangguang area is significantly higher than that in other areas, and the proportion of university affiliated hospitals is also significantly higher than that of non affiliated hospitals 86.6% of the surveyed doctors obtained information through domestic training or conferences, 60.8% through academic journals, and only 28.1% through international conferences or trainings Further analysis shows that the proportion of researchers with international conference or training experience in beishangguang region is significantly higher than that in other regions, and the proportion of university affiliated hospitals is also significantly higher than that of non affiliated hospitals Benefits of participating in research? What are the obstacles? What they value is the value and significance of the research itself, and whether they can learn from it, but they don't pay much attention to improving reputation and getting remuneration They think the biggest obstacle is the lack of time and CRC, and the communication with ethics committee, institutions and sponsors is not a big problem The proportion of doctors who are very interested or interested in participating in clinical research is 67.3% Further research shows that the interest of researchers in beishangguang area in clinical research is significantly lower than that in other areas, and the interest of researchers in non university affiliated hospitals in clinical research is significantly lower than that in university affiliated hospitals The benefits and benefits of clinical research are considered by the investigated doctors as the benefits and benefits of participating in clinical research The top ranked are: contribution to medical development, deepening understanding of disease, opportunity to learn clinical research methods, and providing new treatment for patients It can be seen that what researchers value is the value and significance of participating in research, and whether they can learn and harvest from it In addition, researchers pay more attention to publishing related papers by participating in clinical research However, for improving their reputation by participating in the research and getting paid, ranking at the end shows that a considerable proportion of clinicians do not agree that participating in the clinical research can bring great benefits or benefits in both aspects The difficulties and obstacles of clinical research the doctors surveyed think that the first one is lack of enough time, followed by lack of CRC This is directly related to the current work overload of Chinese doctors and the tedious operation of clinical research itself The third place is the imperfection of clinical trial insurance Many clinical studies in China have not yet purchased special insurance or are not perfect, which brings great risks to clinical research and researchers, especially in the current tense environment of doctor-patient relationship In the fourth place is the systematic support of hospitals The doctor's job is medical treatment, so whether the hospital provides systematic support for doctors to participate in clinical research, including working time arrangement, coordination with their job, relevant policies and training support, is very important for doctors' enthusiasm On the other hand, communication with ethics committee, organization and sponsor is not the main obstacle for researchers to participate in clinical research The regression analysis of the data of the investigated doctors shows that the main factors that affect the interest of Chinese doctors in clinical research are: first, providing new treatment means for patients, second, learning opportunities of clinical research methods, and third, systematic support from hospitals (Ph.D in health and pharmaceutical management, School of pharmacy, Tianjin University)