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Today, the world's serious infectious diseases, such as Ebola virus disease, AIDS, etc., mainly caused by RNA virus.
team led by Zhang Yongzhen, a researcher at the CDC Infectious Diseases Institute of China and an adjunct professor at the Shanghai Public Health Clinical Center affiliated with Fudan University, discovered 214 new RNA viruses, refreshing the scientific community's understanding of the "RNA ring".
scientists' research upended the existing system of virus classification and revealed the genetic evolution of RNA viruses.
Beijing time, the research team's research results in the form of research papers (Research Article) published in the journal Nature.
team also includes CDC researchers from several Chinese cities, Chinese university scholars and scientists from the University of Sydney in Australia.
it is known that RNA viruses differ from THOSE in the composition of genetic material compared to DNA viruses. is
viruses that cause OUTBREAKs such as SARS and Ebola are new? At present, the understanding of the diversity of THE RNA virus esquire and its evolutionary history in vertebrates is still limited to both mammals and birds, and focusing on the small part of the disease can cause disease.
study found that THE RNA virus is actually ancient and not only found in mammals and birds.
it is everywhere in nature, and it is diverse. Zhang Yongzhen,
, said this means that as the ecological geography changes and human lifestyles and behavior patterns change, further research is needed into viruses, especially the presence of a large number of viruses in the oceans that can cause human diseases.
, the team used its highly sensitive pathogen screening system to detect 214 new RNA viruses from 186 vertebrate specimens from China's land, river, lake and ocean.
newly discovered viruses cover all RNA viruses known to infect vertebrates, including viruses that can cause major human diseases, such as influenza viruses, sand granules that cause severe haemorrhagic fever and encephalitis, filamentous viruses that cause Ebola virus disease, and Hantan viruses that cause hemorrhagic fever for kidney syndrome.
, the study suggests that the RNA virus, which is still infecting humans, is actually very old, dating back to the first vertebrate.
researchers' new discovery of the virus in inferior vertebrates exhibits tissue habits similar to those found in mammals. 'This suggests that there are hundreds of millions of years of coevolutionary history between RNA viruses and vertebrate hosts, some of which may represent ancestral patterns in the evolutionary history of the virus, ' said Zhang Yongzhen,
. zhang Yongzhen,
, told reporters that the study has broad significance for analyzing the diversity of viruses and genetic evolution, changing the academic community's previous understanding of the virus circle, and providing a strong basis for the study of the evolution of the origin of life.
Eddie C Holmes, a fellow of the Royal Society of the Australian Academy of Sciences and professor at the University of Sydney who is involved in the study, said the researchers had revealed a new perspective on the evolution of the virus.
says more and more people are beginning to use similar methods to explore other animals, plants and other biota. Zhu Tongyu, director of the Public Health Clinical Center affiliated with Fudan University in
, said the hospital will use the team's microbial discovery and identification capabilities to help the clinical diagnosis of infectious disease pathogens and improve the precise treatment of new and unexplained infectious diseases in China and the world.
.