"Rhodium" and "sulfur" - ligand promoted Rh (III) - catalyzed C-H bond sulfurization

Recently, Professor Sun Weiyin, associate professor of Luyi, School of chemistry and chemical engineering, Nanjing University, and Professor Yu Jinquan of Scripps Research in the United States introduced pentafluorophenylamide as a weak coordination guiding group into the Rh (III) catalytic system, and assisted by ligands to regulate the activity of the Rh (III) catalytic center, realizing the Rh (III) catalytic carbon hydrogen bonded olefin alkylation reaction with air as oxidant (chem SCI., 2015) , 6, 1923), efficient C-H bond arylation (the fastest reaction is completed in 70 minutes) (J org Chem., 2016, 81, 3416), and C-H bond amination involving free amines (angelw Chem Int ed 2017, 56, 7449) The presence of amino acids, BINAP and 2-methylquinoline greatly increased the reaction rate and expanded the range of substrates Recently, on the basis of previous work, the team has made new progress in Rh (III) - catalyzed C-H bond vulcanization by using the regulatory role of amino acid ligands In the catalytic process, the presence of amino acid ligands makes the catalyst keep its activity well in the presence of high concentration of sulfide, which promotes the high efficiency of the reaction This work is mainly completed by Kang Yanshang, a doctoral student The research was supported by NSFC, National Key Laboratory of coordination chemistry and basic research business of Central University The research results were published in Angew Chem Int Ed (DOI: 10.1002/anime.201903511) under the title of "Ligand ‐ Promoted Rh (III) ‐ Catalyzed Thiolation of Benzamides with a Broad Scope of Disulfides Reagents".