RNA interference found to be 'umbrella' for early human neurodevelopment
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Last Update: 2021-03-15
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Source: Internet
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Author: User
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that human neuroresurger cells can use RNA to interfere with antiviral immunity against Zika virus infection, according to a new study by researchers in China. The study is the first to find the crucial role of RNA in the development of antiviral immune mechanisms in human neurodevelopment, and the results were recently published in the internationally renowned journal Cell Research in the form of cover articles.
In this study, a joint research team composed of researchers from Wuhan Virus Research Institute of the Chinese Academy of Sciences, Military Medical Research Institute of the Academy of Military Sciences and Zoological Research Institute of the Chinese Academy of Sciences demonstrated for the first time the important antiviral effect of RNA interference antiviral immunity in human cells, starting with the unique infectious habit of Zika virus to human neuroregenerative cells.
experts believe that the presence of RNA interference with antiviral path paths in human neuroregeneral cells provides a new target for the development of corresponding antiviral drugs. They found that the clinically widely used "old drug" Inosa can enhance the activity of RNA interference in human neuroresurgery cells, showing very effective antiviral effects in human neuroresurgery cells and brain-like organs resulting from differentiation, blocking microcephaly ideomorphages caused by Zika virus infection.
published a commentary on the results of the study by Professor Speyon, a world-renowned virologist, in the same issue of Cell Research. In his article, he evaluates this as a very important advance in RNA interference research.
, RNA interference is an ancient biological phenomenon that is common in organisms and plays a key role in controlling gene expression in organisms, according to experts at the Wuhan Virus Research Institute of the Chinese Academy of Sciences. As an important antiviral immune mechanism in human beings, it has been discovered by a series of researches by scientists in China and Europe and America in recent years. At the same time, RNA interference, as a new biomedical technology, also has a broad application prospect. (Source: Xinhua News Agency, Tan
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