On July 15, the reporter learned from the Institute of Microbiology, Guangdong Academy of Sciences, that the research of the researcher Zhu Honghui's team revealed the adaptive evolution strategy and the latest metabolic engineering targets in the carotenoid synthesis of Saccharomyces cerevisiae
Carotenoids are a large group of naturally occurring colored substances in nature, widely distributed in plants, algae, fungi and bacteria
Based on the known ethanol tolerance mechanism of Saccharomyces cerevisiae (related to cell membranes) and the characteristics of carotenoids stored in the cell membrane, the researchers speculate that the cell membrane may change during the process of improving the ethanol tolerance of Saccharomyces cerevisiae.
"With the help of genomics and transcriptomics, we have successfully identified that PFK1 inactivating mutations are the main reason for the increased carotenoid synthesis ability of mutant strains
Related paper information: https://doi.
https://doi.
org/10.
1186/s40643-021-00402-5
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