Salicylicacid
【Molecular formula and molecular weight】C 7 H 6 O 3 ;138.
12
【Structural formula】
【Source】Organic Synthesis
【Properties】White crystalline powder
This product is soluble in water, easily soluble in ethanol , ether and chloroform
Melting point: 157～159℃
【Purity Check】
TLC
1.
Thin layer plate silica gel G plate
Developing agent cyclohexane- ethyl acetate -formic acid (10:1:1)
After checking the color development of 1% ferric chloride ethanol solution, check under sunlight
2.
Thin layer plate silica gel G plate
Developing agent benzene-acetic acid-methanol (30:1:3)
After checking the color development of 1% ferric chloride ethanol solution, check under sunlight
High performance liquid chromatography
Chromatographic column ZORBAX Eclipse XDB-C 18 column, 5um (4.
6mm×150mm)
The mobile phase methanol - water (78:22) [containing cetyl trimethyl ammonium bromide (HDTA) 0.
0015mol / L, adjusted to pH with dilute acetic acid 5], 1.
0ml / min
Detection wavelength 280nm
[Structural identification] 297, 232, 209
.
3250 (-OH), 2550, 1670 (-C=O), 1610, 1490 (aromatic ring), 1450, 1300, 1250, 1210, 1160, 1030, 890, 760
.
EI-MS m/z: 138[M] +
.
1 H-NMR (CDCl 3 ) δ: 6.
70 (1H, dt, H-4), 7.
01 (1H, dd, H-6), 7.
54 (1H, dt, H-5), 7.
94 (1H, ddd, H -3), 10.
36 (1H, -COOH)
.
13 C-NMR(CDCl 3 ) δ: 111.
2(C-1), 162.
2(C-2), 117.
9(C-3), 137.
0(C-4), 119.
6(C-5), 130.
9(C-6 ), 174.
9(-COOH)
.
【Storage】Dry and airtight
.
Related links: 2,3,5,4'-tetrahydroxystilbene-2-O-β-D-glucoside
