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    Home > Active Ingredient News > Antitumor Therapy > Sci Advs: Study finds new drug for rheumatoid arthritis

    Sci Advs: Study finds new drug for rheumatoid arthritis

    • Last Update: 2022-09-07
    • Source: Internet
    • Author: User
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    On August 19, 2022, Zhang Tiantai's research group, Sun Lan's research group and Zhang Dayong's research group of China Pharmaceutical University published in the journal Science Advances "Science Advances".


    Rheumatoid arthritis (RA) is a chronic systemic disease with unknown etiology, mainly inflammatory synovitis, which can cause joint deformity and loss of function


    Aiming at targeting JAK3 isoforms, the research team designed, synthesized, and screened to obtain a lead compound Z583 that inhibits JAK3 phosphorylation with IC50 of 0.


    Paper link:

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