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    Home > Active Ingredient News > Endocrine System > Science Advances: Apolipoprotein CIII may eliminate metabolic disorders caused by high-fat diet

    Science Advances: Apolipoprotein CIII may eliminate metabolic disorders caused by high-fat diet

    • Last Update: 2021-03-21
    • Source: Internet
    • Author: User
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    As we all know, high fat diet ( HFD ) will not only lead to obesity, but also increase the risk of 2 type diabetes , medsci.


    As we all know, high fat diet ( HFD ) will not only lead to obesity, but also increase the risk of 2 type diabetes , medsci.


    Apolipoprotein CIII ( apoCIII ) is the main apolipoprotein of very low-density lipoprotein cholesterol , and is also present in high-density lipoprotein - cholesterol and low-density lipoprotein - cholesterol.


    Apolipoprotein CIII ( apoCIII ) is very low density lipoprotein cholesterol, the major apolipoprotein, but also in high-density lipoprotein - cholesterol and low density lipoprotein - apolipoprotein CIII ( apoCIII ) is very low density lipoprotein cholesterol of The main apolipoprotein, also present in high-density lipoprotein - cholesterol and low-density lipoprotein - apolipoproteinCIII(apoCIII) isthe main apolipoproteinof very low-density lipoprotein cholesterol , and also present in high-density lipoproteincholesterol-cholesterol And low-density lipoprotein- cholesterol.


    In this study, the researchers studied two groups of mice.


    In this study, the researchers studied two groups of mice.


    The results showed that, after after after 10 weeks of treatment time, the first group of mice all obese, insulin resistant, and liver steatosis.


    In summary, despite the continuous intake of a high-fat diet, reducing apoCIII levels can not only prevent obesity, but also reverse the harmful metabolic disorders caused by fat by increasing insulin sensitivity.


    In summary, despite the continuous intake of high-fat diets, but reducing the continuous intake of high-fat diets, but reducing the continuous intake of high-fat diets, but reducing the level of apoCIII can not only prevent obesity, but also can increase insulin sensitivity.


    Original source

    Ismael Valladolid-Acebes.


    Ismael Valladolid-Acebes.
    et al.
    sciencemag.
    org/content/7/11/eabc2931" target="_blank" rel="noopener">Lowering apolipoprotein CIII protects against high-fat diet–induced metabolic derangements Science Advances (2021).
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    abc2931 Leave a message here
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